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GABARAP 抗体

GABARAP 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN349991
发货至: 中国
  • 抗原 See all GABARAP 抗体
    GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 86
    • 10
    绵羊
    克隆类型
    • 78
    • 18
    多克隆
    标记
    • 33
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    This GABARAP antibody is un-conjugated
    应用范围
    • 62
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    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for GABARAP.
    免疫原
    A synthetic peptide from human GABA(A) receptor-associated protein (GABARAP, MM46, FLC3B) conjugated to an immunogenic carrier protein has been used as the antigen. The antigen is homologous in rat and mouse.
    亚型
    IgG
    Top Product
    Discover our top product GABARAP Primary Antibody
  • 应用备注
    Use at a concentration of 10-50 µg/ml.
    The optimal working concentration should be determined by the end user.
    Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))
    别名
    GABARAP (GABARAP 产品)
    别名
    GABARAP antibody, ATG8A antibody, GABARAP-a antibody, MM46 antibody, gabarap antibody, mg:bb02b03 antibody, GABA type A receptor-associated protein antibody, gamma-aminobutyric acid receptor-associated protein antibody, GABA(A) receptor-associated protein a antibody, gamma-aminobutyric acid receptor associated protein antibody, GABARAP antibody, LOC5568843 antibody, Gabarap antibody, gabarapa antibody
    背景
    Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly.autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels ofautophagy have been described in some malignant tumors, and a role forautophagy in controlling the unregulated cell growth linked to cancer has been proposed. GABARAP belongs ot a large family of proteins that mediate intracellular membrane trafficking and/or fusion. GABARAP binds not only to GABA, type A but also to tubulin, gephrin, and ULK1. May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. It interacts with GPHN and NSF, interacts with GABRG2, beta-tubulin and ULK1.
    Subcellular location: Intracytoplasmic membrane. Cytoplasm, cytoskeleton. Note: Largely associated with intracellular membrane structures including the Golgi apparatus and post-synaptic cisternae. Colocalizes with microtubules.
    Tissue specificity: Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. Also known as: GABA(A) receptor-associated protein, MM46, GABARAP.
    途径
    Autophagy
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