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ATG3 抗体

ATG3 适用: 人 WB, IHC 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN349972
发货至: 中国
  • 抗原 See all ATG3 抗体
    ATG3 (ATG3 Autophagy Related 3 (ATG3))
    适用
    • 114
    • 42
    • 42
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 117
    • 11
    • 2
    绵羊
    克隆类型
    • 110
    • 20
    多克隆
    标记
    • 43
    • 12
    • 12
    • 10
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG3 antibody is un-conjugated
    应用范围
    • 87
    • 55
    • 26
    • 26
    • 19
    • 16
    • 15
    • 14
    • 14
    • 8
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for ATG3.
    交叉反应
    人, 小鼠, 大鼠
    交叉反应 (详细)
    Other species not yet tested.
    纯化方法
    IgG
    免疫原
    A synthetic peptide from human ATG3 conjugated to an immunogenic carrier protein has been used as the antigen. The antigen is homologous in rat and mouse.
    亚型
    IgG
    Top Product
    Discover our top product ATG3 Primary Antibody
  • 应用备注
    IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    ATG3 (ATG3 Autophagy Related 3 (ATG3))
    别名
    ATG3 (ATG3 产品)
    别名
    atg3 antibody, im:6910145 antibody, wu:fb15g12 antibody, zgc:64156 antibody, APG3 antibody, APG3-LIKE antibody, APG3L antibody, PC3-96 antibody, 2610016C12Rik antibody, Apg3l antibody, Atg3l antibody, PIG-1 antibody, Pig1 antibody, ATATG3 antibody, K11J9.1 antibody, K11J9_1 antibody, autophagy related 3 antibody, autophagy 3 (APG3) antibody, similar to S. cerevisiae ATG3 (YNR007C) part of ubiquitin-like system that mediates Atg8-phosphatidylethanolamine conjugation required for protein-vacuolar targeting and autophagy antibody, atg3 antibody, ATG3 antibody, Atg3 antibody
    背景
    Autophagy is a process of bulk degradation of cytoplasmic components by the lysosome or vacuole. Human ATG3 displays the same enzymatic characteristics in vitro as yeast Apg3, a protein-conjugating enzyme essential for autophagy. FUNCTION: GABARAPL1 (GABARAPL2 or GABARAP or MAP1LC3)-modifier protein conjugating enzyme involved in its E2-like covalent binding to PE. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3 (E2-like enzyme). Preferred substrate is MAP1LC3A. Formation of the GABARAPL1-PE conjugate is essential for autophagy. SUBCELLULAR LOCATION: Cytoplasm TISSUE SPECIFICITY: Widely expressed, with a highest expression in heart, skeletal muscle, kidney, liver and placenta.,Mammalian Autophagy,APG3, APG3L, APG3-like
    UniProt
    Q9NT62
    途径
    Autophagy
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