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DPYSL3 抗体 (C-Term)

DPYSL3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN347041
发货至: 中国
  • 抗原 See all DPYSL3 抗体
    DPYSL3 (Dihydropyrimidinase-Like 3 (DPYSL3))
    抗原表位
    • 15
    • 9
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 47
    • 14
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    • 4
    克隆类型
    • 46
    • 2
    多克隆
    标记
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DPYSL3 antibody is un-conjugated
    应用范围
    • 26
    • 20
    • 17
    • 13
    • 13
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    Reacts with 65 kDa CRMP-4 from human rat and mouse
    交叉反应 (详细)
    Do not react with CRMP-1, CRMP-2, CRMP-3 or CRMP-5.
    纯化方法
    Antiserum
    免疫原
    A 15 residue synthetic peptide derived from C-terminal domain of human collapsing-response mediator
    亚型
    IgG
    Top Product
    Discover our top product DPYSL3 Primary Antibody
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    -IHC : 1/500 - WB :1/2 000

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Must be reconstituted in distilled water.
    储存条件
    4 °C/-20 °C
    储存方法
    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    有效期
    24 months
  • Blasco, Bernard-Marissal, Vourch, Guettard, Sunyach, Augereau, Khederchah, Mouzat, Antar, Gordon, Veyrat-Durebex, Besson, Andersen, Salachas, Meininger, Camu, Pettmann, Andres, Corcia: "A rare motor neuron deleterious missense mutation in the DPYSL3 (CRMP4) gene is associated with ALS." in: Human mutation, Vol. 34, Issue 7, pp. 953-60, (2013) (PubMed).

    Bretin, Reibel, Charrier, Maus-Moatti, Auvergnon, Thevenoux, Glowinski, Rogemond, Prémont, Honnorat, Gauchy: "Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain." in: The Journal of comparative neurology, Vol. 486, Issue 1, pp. 1-17, (2005) (PubMed).

    Ricard, Rogemond, Charrier, Aguera, Bagnard, Belin, Thomasset, Honnorat: "Isolation and expression pattern of human Unc-33-like phosphoprotein 6/collapsin response mediator protein 5 (Ulip6/CRMP5): coexistence with Ulip2/CRMP2 in Sema3a- sensitive oligodendrocytes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 18, pp. 7203-14, (2001) (PubMed).

    Honnorat, Byk, Kusters, Aguera, Ricard, Rogemond, Quach, Aunis, Sobel, Mattei, Kolattukudy, Belin, Antoine: "Ulip/CRMP proteins are recognized by autoantibodies in paraneoplastic neurological syndromes." in: The European journal of neuroscience, Vol. 11, Issue 12, pp. 4226-32, (2000) (PubMed).

    Balin, Loewy, Appelt: "Analysis of transglutaminase-catalyzed isopeptide bonds in paired helical filaments and neurofibrillary tangles from Alzheimer's disease." in: Methods in enzymology, Vol. 309, pp. 172-86, (1999) (PubMed).

  • 抗原
    DPYSL3 (Dihydropyrimidinase-Like 3 (DPYSL3))
    别名
    Collapsin Response Mediator Protein 4 (CRMP-4) (DPYSL3 产品)
    别名
    CRMP4A antibody, CRMP4B antibody, dpysl3 antibody, DRP-3 antibody, MGC69487 antibody, dpysl3-b antibody, crmp4 antibody, CRMP-4 antibody, xCRMP4 antibody, DRP-3-B antibody, DPYSL3 antibody, CRMP4 antibody, DRP3 antibody, LCRMP antibody, ULIP antibody, ULIP-1 antibody, TUC4 antibody, Ulip antibody, Ulip1 antibody, Crmp4 antibody, TUC-4b antibody, drp-3 antibody, drp3 antibody, lcrmp antibody, nsp1 antibody, tuc-4 antibody, tuc4 antibody, ulip antibody, ulip-1 antibody, dihydropyrimidinase like 3 antibody, dihydropyrimidinase like 3 L homeolog antibody, dihydropyrimidinase-like 3 antibody, dihydropyrimidinase like 3 S homeolog antibody, DPYSL3 antibody, dpysl3 antibody, dpysl3.L antibody, Dpysl3 antibody, dpysl3.S antibody
    背景
    Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration
    UniProt
    Q14195
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