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Nestin 抗体

NES 适用: 人 WB, IHC, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 10C2 unconjugated
产品编号 ABIN335378
发货至: 中国
  • 抗原 See all Nestin (NES) 抗体
    Nestin (NES)
    适用
    • 129
    • 68
    • 47
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 103
    • 34
    • 4
    • 2
    • 1
    小鼠
    克隆类型
    • 108
    • 36
    单克隆
    标记
    • 62
    • 10
    • 10
    • 9
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    This Nestin antibody is un-conjugated
    应用范围
    • 79
    • 50
    • 48
    • 47
    • 40
    • 39
    • 39
    • 29
    • 25
    • 15
    • 7
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    10C2 reacts exclusively with the human nestin protein. No cross-reactivity to rodent nestin.
    纯化方法
    Purified
    免疫原
    Nestin (clone 10C2) is a monoclonal antibody derived by traditional hybridoma technology. A 150-amino-acid fragment from the cloned human nestin was conjugated to glutathione S-transferase and used as an immunogen.
    克隆位点
    10C2
    亚型
    IgG1
    Top Product
    Discover our top product NES Primary Antibody
  • 限制
    仅限研究用
  • 储存条件
    -20 °C
  • Sellheyer, Krahl: "Does the peritumoral stroma of basal cell carcinoma recapitulate the follicular connective tissue sheath?" in: Journal of cutaneous pathology, Vol. 38, Issue 7, pp. 551-9, (2011) (PubMed).

    Elamin, Shinwari, Hendrayani, Al-Hindi, Al-Shail, Khafaga, Al-Kofide, Aboussekhra: "Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells." in: Molecular carcinogenesis, Vol. 49, Issue 3, pp. 302-14, (2010) (PubMed).

    Popescu, Manole, Gherghiceanu, Ardelean, Nicolescu, Hinescu, Kostin: "Telocytes in human epicardium." in: Journal of cellular and molecular medicine, Vol. 14, Issue 8, pp. 2085-93, (2010) (PubMed).

    Sellheyer, Krahl et al.: "Spatiotemporal expression pattern of neuroepithelial stem cell marker nestin suggests a role in dermal homeostasis, neovasculogenesis, and tumor stroma development: a study on embryonic and adult ..." in: Journal of the American Academy of Dermatology, Vol. 63, Issue 1, pp. 93-113, (2010) (PubMed).

    Murphy, Viero, Ho, Thorner: "Diagnostic utility of nestin expression in pediatric tumors in the region of the kidney." in: Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry, Vol. 17, Issue 6, pp. 517-23, (2009) (PubMed).

    Mokry, Pudil, Ehrmann, Cizkova, Osterreicher, Filip, Kolar: "Re-expression of nestin in the myocardium of postinfarcted patients." in: Virchows Archiv : an international journal of pathology, Vol. 453, Issue 1, pp. 33-41, (2008) (PubMed).

    Corsino, Davis, Nørgaard, Parker, Law, Dunn, Law: "Mammary tumors initiated by constitutive Cdk2 activation contain an invasive basal-like component." in: Neoplasia (New York, N.Y.), Vol. 10, Issue 11, pp. 1240-52, (2008) (PubMed).

    Hou, Tan, Xu, Wang, Lu, Ji, Wang, Zhu: "Schwannoma of the gastrointestinal tract: a clinicopathological, immunohistochemical and ultrastructural study of 33 cases." in: Histopathology, Vol. 48, Issue 5, pp. 536-45, (2006) (PubMed).

    Messam, Hou, Major: "Coexpression of nestin in neural and glial cells in the developing human CNS defined by a human-specific anti-nestin antibody." in: Experimental neurology, Vol. 161, Issue 2, pp. 585-96, (2000) (PubMed).

  • 抗原
    Nestin (NES)
    别名
    Nestin (NES 产品)
    别名
    paranemin antibody, NES antibody, AA166324 antibody, C78523 antibody, ESTM46 antibody, nestin antibody, nestin S homeolog antibody, NES antibody, nes.S antibody, Nes antibody, nes antibody
    背景
    Nestin is a Class IV intermediate filament protein abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. This cytoskeletal protein has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, it is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. These highly specific antibodies to human nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells.
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