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ITGA2 抗体

ITGA2 适用: 人, 猴 FACS, IHC (fro) 宿主: 小鼠 Monoclonal AK7 unconjugated
产品编号 ABIN319765
发货至: 中国
  • 抗原 See all ITGA2 抗体
    ITGA2 (Integrin alpha 2 (ITGA2))
    适用
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    人, 猴
    宿主
    • 82
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    小鼠
    克隆类型
    • 81
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    单克隆
    标记
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    This ITGA2 antibody is un-conjugated
    应用范围
    • 66
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognises the integrin alpha 2 subunit, which is 160 kDa cell surface antigen expressed by NK cells and a small subset of T-cells. This antibody inhibits cell attachment to collagen.
    纯化方法
    Affinity Chromatography on Protein G.
    免疫原
    Spleen cells from immunised mice were fused with cells of the mouse NS1 myeloma cell line.
    克隆位点
    AK7
    亚型
    IgG1
    Top Product
    Discover our top product ITGA2 Primary Antibody
  • 应用备注
    Flow Cytometry: 1/50-1/100, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry on Frozen Sections: 1/500-1/1000. Recommended positive control tissue: Tonsil.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ITGA2 (Integrin alpha 2 (ITGA2))
    别名
    CD49b / ITGA2 (ITGA2 产品)
    别名
    BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody
    背景
    Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2
    基因ID
    3673
    NCBI登录号
    NP_002194
    UniProt
    P17301
    途径
    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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