CASP5 抗体
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- 抗原 See all CASP5 抗体
- CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CASP5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 特异性
- This antibody recognises an epitope located within the internal region of human Caspase-5, a 47 kDa cysteine protease, otherwise known as ICH-3.
- 纯化方法
- Antisera to human Caspase-5 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- 免疫原
- A 14 amino acid peptide from the centre of human Caspase-5.
- 亚型
- IgG
- Top Product
- Discover our top product CASP5 Primary Antibody
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anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (AA 145-327) antibody
CASP5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (AA 162-191) antibodyCASP5 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (AA 162-191) antibodyCASP5 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18988 unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) antibodyCASP5 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (AA 146-175), (Middle Region) antibodyCASP5 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) antibodyCASP5 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (Cleaved-Ser331) antibodyCASP5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (Cleaved-Asp121) antibodyCASP5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (AA 251-300) antibodyCASP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (Middle Region) antibodyCASP5 适用: 人, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1.0g/mL - 2.0g/mL, detects a band of approximately 48 kDa in Ramos celllysates. (Predicted precursor MWT 47.8 kDa)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline containing 0.02 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
- 别名
- Caspase-5 (CASP5 产品)
- 别名
- ICE(rel)III antibody, ICEREL-III antibody, ICH-3 antibody, CASP5 antibody, caspase 5 antibody, caspase-5 antibody, CASP5 antibody, LOC100437308 antibody
- 背景
- Caspase-5 has been shown to be expressed at higher levels in the colon, lung, spleen, small intestine and by peripheral blood lymphocytes. Caspase-5 is a member of a growing number of inflammatory caspases belonging to the Caspase-1 (ICE-type) subfamily, which require proteolytic processing of their inactive precursor into smaller active subunits. Unlike Caspase-1, Caspase-5 is not directly responsible for the activation of IL-1Beta from the pro-IL-1Beta precursor, but the presence of Caspase-5 does appear to enhance the processing of IL-1Beta. The in vivo expression of Caspase-5 is elevated by Lipopolysaccharide (LPS) and gene expression is also increased by Interferon gamma (IFNg). In vitro studies have shown cleavage of Caspase-5 by the serine protease Granzyme B, which plays a major role in Cytotoxic T lymphocyte (CTL)-induced apoptosis (1).Synonyms: CASP-5, CASP5, ICE(rel)-III, ICH-3 protease, ICH3, TY protease
- 基因ID
- 838
- NCBI登录号
- NP_001129581
- UniProt
- P51878
- 途径
- Inflammasome
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