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CCR8 抗体 (AA 183-201)

CCR8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN319016
发货至: 中国
  • 抗原 See all CCR8 抗体
    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
    抗原表位
    • 14
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 183-201
    适用
    • 49
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 43
    • 5
    • 4
    • 1
    克隆类型
    • 46
    • 7
    多克隆
    标记
    • 33
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR8 antibody is un-conjugated
    应用范围
    • 35
    • 28
    • 22
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody recognises the chemokine receptor CCR8, also known as CDw198, which has been identified as a co-receptor for HIV infection. CCR8 is a receptor for the human chemokine 1-309 which is expressed on spleen, thymus and T lymphoblastic cell lines. This antibody detects a band of approximately 50 kDa.
    纯化方法
    Purified
    免疫原
    Peptide corresponding to amino acids 183 to 201 of human CDw198 (CCR8).
    亚型
    IgG
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    Discover our top product CCR8 Primary Antibody
  • 应用备注
    Western Blot: 1: 500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate buffered saline containing 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
    别名
    CDw198 / CCR8 (CCR8 产品)
    别名
    CC-CKR-8 antibody, CCR-8 antibody, CDw198 antibody, CKRL1 antibody, CMKBR8 antibody, CMKBRL2 antibody, CY6 antibody, GPRCY6 antibody, TER1 antibody, C-C antibody, C-C CKR-8 antibody, CKR-8 antibody, Cmkbr8 antibody, mCCR8 antibody, C-C motif chemokine receptor 8 antibody, chemokine (C-C motif) receptor 8 antibody, CCR8 antibody, Ccr8 antibody
    背景
    CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation regulated cytokine (TARC) and macrophage inflammatory protein 1 beta (MIP1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. CCR8 expression has been reported in spleen and thymus, natural killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes. CCR8 is also believed to be alternative coreceptor with CD4 for HIV-1 infection.Synonyms: C-C CKR-8, C-C chemokine receptor type 8, CC-CKR-8, CC-chemokine receptor CHEMR1, CCR-8, CKRL1, CMKBR8, CMKBRL2, Chemokine receptor-like 1, GPR-CY6, TER1
    基因ID
    1237
    NCBI登录号
    NP_005192
    UniProt
    P51685
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