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FLIP 抗体 (C-Term)

CFLAR 适用: 人, 小鼠 WB, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318973
发货至: 中国
  • 抗原 See all FLIP (CFLAR) 抗体
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    抗原表位
    • 16
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    AA 191-209, C-Term
    适用
    • 95
    • 66
    • 57
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 85
    • 15
    • 2
    克隆类型
    • 87
    • 15
    多克隆
    标记
    • 54
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    This FLIP antibody is un-conjugated
    应用范围
    • 97
    • 39
    • 27
    • 26
    • 21
    • 20
    • 14
    • 14
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    • 9
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognises the apoptosis related protein designated FLIP (FLICE inhibitory protein).
    纯化方法
    Purified
    免疫原
    A peptide corresponding to aa191 - 209 at the C-terminus of human FLIP delta/FLIPs form.
    亚型
    IgG
    Top Product
    Discover our top product CFLAR Primary Antibody
  • 应用备注
    Immunohistochemistry on frozen sections: 2g/mL. Western Blot: 1: 1000, detects bands of approximately 35 kDa and 25 kDa in Jurkat celllysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline containing 0.02 % Sodium Azide (NaN3)
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    别名
    CFLAR / Casper / I-FLICE (CFLAR 产品)
    别名
    Clarp1 antibody, cflar antibody, CFLAR antibody, FLIP antibody, CASH antibody, CASP8AP1 antibody, CLARP antibody, Casper antibody, FLAME antibody, FLAME-1 antibody, FLAME1 antibody, I-FLICE antibody, MRIT antibody, c-FLIP antibody, c-FLIPL antibody, c-FLIPR antibody, c-FLIPS antibody, 2310024N18Rik antibody, A430105C05Rik antibody, Cash antibody, ENSMUSG00000072980 antibody, Flip antibody, Gm9845 antibody, c-Flip antibody, CASP8 and FADD-like apoptosis regulator a antibody, CASP8 and FADD like apoptosis regulator antibody, CASP8 and FADD like apoptosis regulator S homeolog antibody, CASP8 and FADD-like apoptosis regulator antibody, cflara antibody, CFLAR antibody, cflar antibody, cflar.S antibody, Cflar antibody
    背景
    FLIP interacts with the adaptor protein FADD, and with Caspase-8 (FLICE) and Caspase-10 (FLICE2) to inhibit apoptosis induced by death receptors including CD95, DR3, TRAIL-R and TNFR1. FLICE inhibitory proteins were initially identified in virus and human and were accordingly designated as v-FLIPs and c-FLIPs. Four spice variants of c-FLIP have been identified and are classified as FLIP alpha, beta, delta and gamma. AHP1591 recognizes human and murine delta and gamma variants but not the alpha or beta, variants. FLIP is widely expressed in human tissues and a diverse range of cell lines.Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
    基因ID
    8837
    NCBI登录号
    NP_001120655
    UniProt
    O15519
    途径
    Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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