ORAI3 抗体 (N-Term)
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- 抗原 See all ORAI3 抗体
- ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
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抗原表位
- N-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ORAI3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody recognises human ORAI3, also known as Transmembrane protein 142C (TMEM142C), a 31.5 kDa multi-pass membrane protein belonging to the ORAI family. This antibody is not expected to cross react with either ORAI1 or ORAI2.
- 纯化方法
- Purified
- 免疫原
- A 15 amino acid peptide from near the amino terminus of human ORAI3.
- 亚型
- IgG
- Top Product
- Discover our top product ORAI3 Primary Antibody
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anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibody
ORAI3 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (AA 1-30) antibodyORAI3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibodyORAI3 适用: 人, 大鼠 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 2H2G9 unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (N-Term) antibodyORAI3 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibodyORAI3 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry on frozen sections: 10g/mL. Western Blot: 1 - 2g/mL, detects a band of approximately 35 kDa in A20 cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline containing 0.02 % Sodium Azide (NaN3)
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 储存条件
- 4 °C
- 储存方法
- Store at +4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted.
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- 抗原
- ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
- 别名
- ORAI3 (ORAI3 产品)
- 别名
- ORAI3 antibody, TMEM142C antibody, 9930124N15 antibody, BC061259 antibody, Tmem142c antibody, RGD1306538 antibody, ORAI calcium release-activated calcium modulator 3 antibody, ORAI3 antibody, Orai3 antibody
- 背景
- Antigen stimulation of immune cells triggers Ca2+ entry through Ca2+ release-activated Ca2+ (CRAC) channels. CRAC channels are the main pathway for Ca2+ influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT. ORAI3 is one of two mammalian homologs of ORAI1, a four- transmembrane spanning protein that is an essential component of CRAC channels. ORAI3, along with ORAI1 and ORAI2, functions as a Ca2+ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca2+ sensor. Studies indicate that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2.Synonyms: ORAI-3, TMEM142C, Transmembrane Protein 142C
- 基因ID
- 93129
- NCBI登录号
- NP_689501
- UniProt
- Q9BRQ5
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