PAK2 抗体 (C-Term)
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- 抗原 See all PAK2 抗体
- PAK2 (P21-Activated Kinase 2 (PAK2))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody recognises p21-activated kinase-2 (PAK2).
- 纯化方法
- Purified
- 免疫原
- 14 amino acid peptide sequence near the carboxy terminus of human PAK2
- 亚型
- IgG
- Top Product
- Discover our top product PAK2 Primary Antibody
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anti-P21-Activated Kinase 2 (PAK2) (AA 131-230) antibody
PAK2 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-P21-Activated Kinase 2 (PAK2) antibodyPAK2 适用: 人, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-P21-Activated Kinase 2 (PAK2) (AA 1-212) antibodyPAK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 2 (PAK2) antibodyPAK2 适用: 人 WB, ELISA, IP, FACS 宿主: 兔 Monoclonal 6D12 unconjugated Recombinant Antibody
anti-P21-Activated Kinase 2 (PAK2) (AA 177-419) antibodyPAK2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 2 (PAK2) (pThr402) antibodyPAK2 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 2 (PAK2) (AA 192-222) antibodyPAK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 2 (PAK2) (N-Term) antibodyPAK2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 2 (PAK2) (pSer20) antibodyPAK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 2 (PAK2) (Ser62) antibodyPAK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 58 kDa in Jurkat cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline containing 0.02 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- PAK2 (P21-Activated Kinase 2 (PAK2))
- 别名
- PAK2 (PAK2 产品)
- 别名
- PAK65 antibody, PAKgamma antibody, gamma-PAK antibody, 5330420P17Rik antibody, A130002K10Rik antibody, AI836325 antibody, D16Ertd269e antibody, PAK-2 antibody, mKIAA4182 antibody, pak2 antibody, cb422 antibody, kinase antibody, zgc:91798 antibody, wu:fb71h01 antibody, si:dz198m22.1 antibody, pak65 antibody, pakgamma antibody, PAKI antibody, Pak3 antibody, CH73-159L23.1 antibody, wu:fc52b03 antibody, zgc:113857 antibody, p21 (RAC1) activated kinase 2 antibody, p21 protein (Cdc42/Rac)-activated kinase 2 antibody, p21 protein (Cdc42/Rac)-activated kinase 2a antibody, p21 protein (Cdc42/Rac)-activated kinase 2 S homeolog antibody, p21 protein (Cdc42/Rac)-activated kinase 2b antibody, PAK2 antibody, Pak2 antibody, pak2a antibody, pak2.S antibody, pak2b antibody
- 背景
- PAK2 is a ubiquitously expressed, 64 kDa, serine/threonine protease found at higher levels in skeletal muscle, ovary, thymus and spleen. p21-activated kinases (PAKs) bind activated Cdc42 and Rac via a Cdc42/Rac interactive binding (CRIB) domain. Group 1 PAK kinases (PAK1, 2 and 3) regulate the activity of an adjacent conserved autoinhibitory domain and are associated with cellular processes, including cytoskeleton rearrangement, apoptosis and MAP kinase signalling. Group 2 PAKs (PAK4, 5, and 6) lack the autoinhibitory domain and are not activated by Cdc42/Rac binding. PAK2 has a cytostatic effect on cells and is activated in response to cellular stresses such hyperosmolarity, serum starvation, contact inhibition and DNA damage from radiation and chemicals. Unlike other PAKs, PAK2 can be activated by proteolytic cleavage to generate a constitutively active fragment, PAK2p34, which induces a cell death response. This induction is thought to be regulated by Rho GTPase-activating protein 10 which inhibits the protein kinase activity of PAK2p34 and causes it to localise to the perinuclear region instead of the nucleus. PAK2 may also play a role in X-linked mental retardation.Synonyms: Gamma-PAK, PAK 2, PAK gamma, PAK-2, PAK65, Serine/threonine-protein kinase PAK 2, p21-activated kinase 2, p58
- 基因ID
- 5062
- NCBI登录号
- NP_002568
- UniProt
- Q13177
- 途径
- MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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