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BMI1 抗体 (Middle Region)

BMI1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318769
发货至: 中国
  • 抗原 See all BMI1 抗体
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    抗原表位
    • 14
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 110
    • 47
    • 26
    • 11
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 77
    • 31
    • 6
    克隆类型
    • 78
    • 36
    多克隆
    标记
    • 77
    • 8
    • 8
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BMI1 antibody is un-conjugated
    应用范围
    • 91
    • 49
    • 40
    • 20
    • 14
    • 13
    • 11
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody recognises 37 kDa polycomb complex protein BMI-1, involved in segment specification, cell growth and maintenance, transcriptional regulation and chromatin modification.
    纯化方法
    Purified
    免疫原
    15 amino acid peptide sequence near the centre of human BMI-1.
    亚型
    IgG
    Top Product
    Discover our top product BMI1 Primary Antibody
  • 应用备注
    Western Blot: 0.5 - 1.0g/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline containing 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    别名
    BMI-1 / RNF51 (BMI1 产品)
    别名
    FLVI2/BMI1 antibody, PCGF4 antibody, RNF51 antibody, AW546694 antibody, Bmi-1 antibody, Pcgf4 antibody, bmi1 antibody, pcgf4 antibody, psc1 antibody, wu:fb17g03 antibody, wu:fd18f06 antibody, BMI-1 antibody, pcgf4b antibody, bmi-1 antibody, bmi1-a antibody, bmi1-b antibody, bmi1b antibody, rnf51 antibody, xbmi-1 antibody, BMI1 proto-oncogene, polycomb ring finger antibody, BMI1 polycomb ring finger oncogene antibody, Bmi1 polycomb ring finger oncogene antibody, bmi1 polycomb ring finger oncogene 1a antibody, bmi1 polycomb ring finger oncogene 1b antibody, BMI1 proto-oncogene, polycomb ring finger L homeolog antibody, BMI1 antibody, LOC100230513 antibody, Bmi1 antibody, bmi1a antibody, bmi1b antibody, bmi1.L antibody
    背景
    BMI-1 is a proto-oncogene which cooperates with the myc oncogene to produce B-lymphomas. It is required in the regulation of normal adult and leukaemic stem cells, making BMI-1 a potential target for stem cell proliferation and anti-cancer therapies. BMI-1 represses transcription at the ink4 locus which contains tumour suppressors p16 and p19Arf. BMI-1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex which ubiquitinates histone-2A at lys119, resulting in a heritable change in the ability of chromatin to express genes. BMI-1 is also required to stimulate the E3 ubiquitin ligase activity of RNF2/RING2 within the PRC1 complex.Synonyms: BMI1, PCGF4, Polycomb group RING finger protein 4, RING finger protein 51
    基因ID
    100532731
    NCBI登录号
    NP_001190991
    UniProt
    P35226
    途径
    Cell Division Cycle, Autophagy
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