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ERN1 抗体 (C-Term)

ERN1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN318702
发货至: 中国
  • 抗原 See all ERN1 抗体
    ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
    抗原表位
    • 16
    • 16
    • 15
    • 13
    • 7
    • 7
    • 7
    • 6
    • 6
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    • 5
    • 5
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 103
    • 78
    • 74
    • 16
    • 1
    人, 小鼠, 大鼠
    宿主
    • 107
    • 4
    • 3
    • 1
    克隆类型
    • 109
    • 6
    多克隆
    标记
    • 33
    • 11
    • 10
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    This ERN1 antibody is un-conjugated
    应用范围
    • 82
    • 44
    • 29
    • 26
    • 26
    • 10
    • 9
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognises inositol-requiring kinase 1 precursor (IRE1p).
    纯化方法
    Affinity Chromatography
    免疫原
    A 16 amino acid peptide near the carboxy terminus of Human IRE1p
    亚型
    IgG
    Top Product
    Discover our top product ERN1 Primary Antibody
  • 应用备注
    Western blot: 1 - 2 μg/mL (detects a band of approximately 110 kDa in A-20 cell lysate).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
    别名
    ERN1 / IRE1 (ERN1 产品)
    别名
    IRE1 antibody, IRE1P antibody, IRE1a antibody, hIRE1p antibody, 9030414B18Rik antibody, AI225830 antibody, C85377 antibody, Ire1a antibody, Ire1alpha antibody, Ire1p antibody, RGD1559716 antibody, Ern1 antibody, Ire1 antibody, Ire1b antibody, sb:eu1005 antibody, zgc:109932 antibody, endoplasmic reticulum to nucleus signaling 1 antibody, endoplasmic reticulum to nucleus signaling 2 antibody, endoplasmic reticulum (ER) to nucleus signalling 1 antibody, serine/threonine-protein kinase/endoribonuclease IRE1 antibody, endoplasmic reticulum (ER) to nucleus signalling 2 antibody, ERN1 antibody, ERN2 antibody, Ern1 antibody, LOC524719 antibody, Ern2 antibody, ern1 antibody
    背景
    Inositol-requiring kinase 1 precursor (IRE1p) is a 108 kDa serine-threonine kinase/endoribonuclease also known as ERN1. It is an endoplasmic reticulum (ER) transmembrane protein, normally bound to the ER molecular chaperones GRP78 and GRP94. At times of ER stress, due to accumulation of unfolded proteins, IRE1p becomes dissociated from the chaperones, which allows it to activate the un-folded protein transcriptional response (UPR). In the mammalian genome, there are two homologs Ire1alpha and Ire1beta. Ire1alpha is expressed in all cells and tissues, Ire1beta expression is primarily restricted to intestinal epithelial cells.Synonyms: Endoplasmic reticulum-to-nucleus signaling 1, IRE1a, IRE1p, Inositol-requiring protein 1, Ire1-alpha, Serine/threonine-protein kinase/endoribonuclease IRE1
    基因ID
    2081
    NCBI登录号
    NP_001424
    UniProt
    O75460
    途径
    ER-Nucleus Signaling, Unfolded Protein Response
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