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ABCC10 抗体

ABCC10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317845
发货至: 中国
  • 抗原 See all ABCC10 抗体
    ABCC10 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10))
    适用
    • 45
    • 2
    • 1
    宿主
    • 39
    • 4
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    • 1
    克隆类型
    • 42
    • 4
    多克隆
    标记
    • 22
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    • 1
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    This ABCC10 antibody is un-conjugated
    应用范围
    • 45
    • 22
    • 17
    • 14
    • 13
    • 13
    • 6
    • 4
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    • 2
    • 1
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    Western Blotting (WB)
    特异性
    MRP7 antibody detects endogenous levels of MRP7 protein.(region surrounding Glu865)
    纯化方法
    Affinity chromatography
    Top Product
    Discover our top product ABCC10 Primary Antibody
  • 应用备注
    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ABCC10 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10))
    别名
    ABCC10 / MRP7 (ABCC10 产品)
    别名
    EST182763 antibody, MRP7 antibody, SIMRP7 antibody, Mrp7 antibody, mFLJ00002 antibody, ATP binding cassette subfamily C member 10 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 10 antibody, ABCC10 antibody, Abcc10 antibody
    背景
    The MRP family is represented by nine similar ABC transporters that have the ability to transport structurally diverse lipophilic anions and operate as chemical efflux pumps. MRP7 (multidrug resistance-associated protein 7, ATPbinding cassette sub-family C member 10) is a multi-pass membrane protein that belongs to the ABC transporter family (conjugate transporter subfamily). MRP7 is involved with the ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG). MRP7 is also probably involved in cellular detoxification through its lipophilic anion extrusion capabilities. MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains. MRP7 likely has three isoforms. Isoform 2 is the most widely expressed, while isoform 1 is predominately expressed in the spleen.Synonyms: ATP-binding cassette, Multidrug resistance-associated protein 7, SIMRP7, member 10, sub-family C
    分子量
    approx. 162 kDa
    基因ID
    89845
    NCBI登录号
    NP_001185863
    UniProt
    Q5T3U5
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