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NTSR2 抗体

NTSR2 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317761
发货至: 中国
  • 抗原 See all NTSR2 抗体
    NTSR2 (Neurotensin Receptor 2 (NTSR2))
    适用
    • 34
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    人, 小鼠, 大鼠
    宿主
    • 51
    克隆类型
    • 51
    多克隆
    标记
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    • 2
    • 1
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    This NTSR2 antibody is un-conjugated
    应用范围
    • 37
    • 14
    • 13
    • 13
    • 8
    • 8
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    NTR2 antibody detects endogenous levels of NTR2 protein.(region surrounding Asp184)
    纯化方法
    Affinity chromatography
    Top Product
    Discover our top product NTSR2 Primary Antibody
  • 应用备注
    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NTSR2 (Neurotensin Receptor 2 (NTSR2))
    别名
    Neurotensin Receptor Type 2 (NTSR2 产品)
    别名
    NTSR2 antibody, NTR2 antibody, NT2R antibody, NTRL antibody, neurotensin receptor 2 antibody, NTSR2 antibody, Ntsr2 antibody
    背景
    Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is coexpressed with the full length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1β and TNFα in an ERK1/2 and Akt kinase-dependent manner.Synonyms: Levocabastine-sensitive neurotensin receptor, NT-R-2, NTR2, NTSR2
    分子量
    approx. 45 kDa
    基因ID
    23620
    NCBI登录号
    NP_036476
    UniProt
    O95665
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