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TARDBP 抗体 (N-Term)

TARDBP 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal k1B8 unconjugated
产品编号 ABIN317572
发货至: 中国
  • 抗原 See all TARDBP 抗体
    TARDBP (TAR DNA Binding Protein (TARDBP))
    抗原表位
    • 15
    • 11
    • 11
    • 9
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-260, N-Term
    适用
    • 100
    • 59
    • 59
    • 13
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    宿主
    • 103
    • 13
    • 1
    小鼠
    克隆类型
    • 94
    • 23
    单克隆
    标记
    • 64
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TARDBP antibody is un-conjugated
    应用范围
    • 85
    • 47
    • 34
    • 32
    • 21
    • 17
    • 14
    • 13
    • 13
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    The antibody recognizes Human TARDBP. Other species not tested.
    产品特性
    Synonyms: TDP43, TDP-43, TAR DNA-binding protein 43
    纯化方法
    Protein-G Affinity Chromatography
    免疫原
    Recombinant Human TARDBP (1-260 aa) purified from E. coli.
    克隆位点
    K1B8
    亚型
    IgG1
    Top Product
    Discover our top product TARDBP Primary Antibody
  • 应用备注
    ELISA. Western blot (1/1,000-1/2,000). Immunohistochemistry on Paraffin Sections (1/50-1/100).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    TARDBP (TAR DNA Binding Protein (TARDBP))
    别名
    TARDBP (TARDBP 产品)
    别名
    TARDBP antibody, TDP43 antibody, DKFZp459I2127 antibody, tardbp antibody, ALS10 antibody, TDP-43 antibody, 1190002A23Rik antibody, C85084 antibody, Tdp43 antibody, wu:fb77f02 antibody, wu:fc52g10 antibody, TAR DNA binding protein antibody, Tardbp protein antibody, TAR DNA binding protein L homeolog antibody, TAR DNA-binding protein 43-like antibody, TARDBP antibody, tardbp antibody, tardbp.L antibody, Tardbp antibody, LOC100621383 antibody
    背景
    TAR DNA binding protein (TARDBP), also known as TDP-43, is a cellular protein. TARDBP was identified as the disease accumulating protein in patients with frontotemporal lobar degeneration (FTLD) with ubiquitin inclusions (FTLD-U) and in amyotrophic lateral sclerosis (ALS). TARDBP functions as a DNA-binding protein and specifically binds to the TAR DNA sequence motifs of HIV. Via this association with TAR motifs, TARDBP acts as a transcriptional repressor and inhibits HIV-1 transcription. In addition, this protein regulates alternate splicing of the cystic fibrosis transmembrane receptor (CFTR) gene.Synonyms: TAR DNA-binding protein 43, TDP-43, TDP43
    基因ID
    23435
    UniProt
    Q13148
    途径
    Positive Regulation of Peptide Hormone Secretion
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