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ATG5 抗体 (C-Term)

ATG5 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 马, 兔, 豚鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN311668
发货至: 中国
  • 抗原 See all ATG5 抗体
    ATG5 (ATG5 Autophagy Related 5 (ATG5))
    抗原表位
    • 16
    • 13
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 103
    • 44
    • 36
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 斑马鱼, 马, 兔, 豚鼠, 犬
    宿主
    • 78
    • 22
    • 4
    • 1
    克隆类型
    • 77
    • 28
    多克隆
    标记
    • 58
    • 8
    • 7
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG5 antibody is un-conjugated
    应用范围
    • 80
    • 54
    • 36
    • 19
    • 18
    • 17
    • 14
    • 13
    • 10
    • 10
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    DPEDGEKKNQ VMIHGIEPML ETPLQWLSEH LSYPDNFLHI SIIPQPTD
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against ATG5. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human ATG5
    Top Product
    Discover our top product ATG5 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 275 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原
    ATG5 (ATG5 Autophagy Related 5 (ATG5))
    别名
    ATG5 (ATG5 产品)
    别名
    APG5 antibody, APG5-LIKE antibody, APG5L antibody, ASP antibody, hAPG5 antibody, ATG5 antibody, CG1643 antibody, DmAtg5 antibody, Dmel\\CG1643 antibody, atg5 antibody, 2010107M05Rik antibody, 3110067M24Rik antibody, AW319544 antibody, Apg5l antibody, Atg5l antibody, C88337 antibody, Paddy antibody, apg5l antibody, zgc:100934 antibody, ATATG5 antibody, AUTOPHAGY 5 antibody, MKP11.20 antibody, MKP11_20 antibody, autophagy related 5 antibody, Autophagy-related 5 antibody, ATG5 autophagy related 5 homolog (S. cerevisiae) antibody, autophagy related 5 L homeolog antibody, similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12 antibody, autophagy protein Apg5 family antibody, ATG5 antibody, Atg5 antibody, atg5 antibody, atg5.L antibody, APG5 antibody
    背景
    ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 may play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
    Alias Symbols: APG5, APG5L, ASP, hAPG5, APG5-LIKE
    Protein Interaction Partner: TEKT4, CCHCR1, WIPI2, KEAP1, VCP, MEOX2, FADD, ATG16L1, RB1CC1, EXOC4, ATG3, ATG12, CAV1, HTT, WDFY3, TAB3, TAB2, TECPR1, ELAVL1, UBC, SIRT1, TKT, MAP1LC3C, MAP1LC3B, ATG10, ATG5, IMPDH2,
    Protein Size: 275
    分子量
    32 kDa
    基因ID
    9474
    NCBI登录号
    NM_004849, NP_004840
    UniProt
    Q9H1Y0
    途径
    Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
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