SEMA6D 抗体 (N-Term)
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Quick Overview for SEMA6D 抗体 (N-Term) (ABIN311204)
抗原
See all SEMA6D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VSFPEDDEPL NTVDYHYSRQ YPVFRGRPSG NESQHRLDFQ LMLKIRDTLY
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against SEMA6D. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human SEMA6D
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anti-Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D) (N-Term) antibody
SEMA6D 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D) (AA 1-476) antibodySEMA6D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D) (AA 913-1068) antibodySEMA6D 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D) (AA 1-476) antibodySEMA6D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D) antibodySEMA6D 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D) (AA 21-70) antibodySEMA6D 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠, Pig, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D) (AA 182-231) antibodySEMA6D 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, Pig, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D) (N-Term) antibodySEMA6D 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D) (C-Term) antibodySEMA6D 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D) (AA 19-48), (N-Term) antibodySEMA6D 适用: 人 WB 宿主: 兔 Polyclonal RB32830 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 476 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2." in: Genes & development, Vol. 18, Issue 4, pp. 435-47, (2004) (PubMed).
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- SEMA6D (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D))
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别名
- SEMA6D
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背景
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Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.
Alias Symbols: FLJ11598, KIAA1479
Protein Interaction Partner: PLXNA1,
Protein Size: 476 -
分子量
- 52 kDa
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基因ID
- 80031
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NCBI登录号
- NM_024966, NP_079242
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UniProt
- Q8NFY4
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途径
- Smooth Muscle Cell Migration
抗原
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