电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

MAFK 抗体 (N-Term)

MAFK 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 斑马鱼, 犬, 马, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN310919
发货至: 中国
  • 抗原 See all MAFK 抗体
    MAFK (Transcription Factor MafK (MAFK))
    抗原表位
    • 7
    • 6
    • 6
    • 3
    N-Term
    适用
    • 27
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 豚鼠, 斑马鱼, 犬, 马, 兔, 绵羊
    宿主
    • 25
    • 2
    克隆类型
    • 25
    • 2
    多克隆
    标记
    • 12
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This MAFK antibody is un-conjugated
    应用范围
    • 21
    • 16
    • 14
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    KEAGENAPVL SDDELVSMSV RELNQHLRGL TKEEVTRLKQ RRRTLKNRGY
    预测反应
    Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 79%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against MAFK. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human MAFK
    Top Product
    Discover our top product MAFK Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 156 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MAFK (Transcription Factor MafK (MAFK))
    别名
    MAFK (MAFK 产品)
    别名
    NFE2U antibody, P18 antibody, AW061068 antibody, NF-E2 antibody, Nfe2u antibody, MAF bZIP transcription factor K antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K antibody, Mafk antibody, MAFK antibody, mafk antibody
    背景
    The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2. NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, PBGD and FECH. NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of bZIP proteins. Maf homodimers suppress transcription at NFE2 sites.The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD, MIM 176000) and ferrochelatase (FECH, MIM 177000). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM].
    Alias Symbols: FLJ32205, MGC71717, NFE2U, P18
    Protein Interaction Partner: NFE2L2, SMAD3, PARP1, HIF1A, UBC, SUMO2, Bach1, HDAC3, HDAC2, HDAC1, CREBBP, RELA, KAT6A, TP53, BACH2, NFE2L3, NFE2, MARS, MAFK, NFE2L1, HOXD12,
    Protein Size: 156
    分子量
    17 kDa
    基因ID
    7975
    NCBI登录号
    NM_002360, NP_002351
    UniProt
    O60675
You are here:
客服