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- 抗原 See all MRPS12 抗体
- MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))
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抗原表位
- N-Term
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适用
- 人, 大鼠, Cow, 犬, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MRPS12 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LVPRLWATCS MATLNQMHRL GPPKRPPRKL GPTEGRPQLK GVVLCTFTRK
- 预测反应
- Cow: 86%, Dog: 91%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against MRPS12. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MRPS12
- Top Product
- Discover our top product MRPS12 Primary Antibody
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anti-Mitochondrial Ribosomal Protein S12 (MRPS12) (Internal Region) antibody
MRPS12 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Ribosomal Protein S12 (MRPS12) (Internal Region) antibodyMRPS12 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Ribosomal Protein S12 (MRPS12) (AA 20-69) antibodyMRPS12 适用: 人, 大鼠, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrial Ribosomal Protein S12 (MRPS12) (AA 1-138) antibodyMRPS12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mitochondrial Ribosomal Protein S12 (MRPS12) (AA 28-59) antibodyMRPS12 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB17455 unconjugated
anti-Mitochondrial Ribosomal Protein S12 (MRPS12) (AA 35-67), (Middle Region) antibodyMRPS12 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 138 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MRPS12 (Mitochondrial Ribosomal Protein S12 (MRPS12))
- 别名
- MRPS12 (MRPS12 产品)
- 别名
- MPR-S12 antibody, MT-RPS12 antibody, RPMS12 antibody, RPS12 antibody, RPSM12 antibody, AI327385 antibody, Rpms12 antibody, rps12 antibody, CG7925 antibody, Dmel\\CG7925 antibody, EG:BACH59J11.1 antibody, MRP-S12 antibody, MRPS12 antibody, S12 antibody, Tko antibody, l(1)3Ab antibody, l(1)tko antibody, mRpS12 antibody, mt-rps12 antibody, MGC64304 antibody, GB10531 antibody, mitochondrial ribosomal protein S12 antibody, technical knockout antibody, mitochondrial ribosomal protein S12 L homeolog antibody, 40S ribosomal protein S12, mitochondrial antibody, putative mitochondrial 37S ribosomal protein MRPS12 antibody, fragile site, aphidicolin type, common, fra(6)(p22.2) antibody, MRPS12 antibody, Mrps12 antibody, tko antibody, mrps12.L antibody, LOC409723 antibody, mRpS12 antibody, mrps12 antibody, CAALFM_C106070WA antibody, mrpS12 antibody, FRA6C antibody
- 背景
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Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPS12 is the 28S subunit protein that belongs to the ribosomal protein S12P family. The protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics.Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene, all three variants encode the same protein.
Alias Symbols: MPR-S12, MT-RPS12, RPMS12, RPS12, RPSM12
Protein Interaction Partner: UBC, LRIF1, SPINK7, C14orf1, UNC119, CRMP1,
Protein Size: 138 - 分子量
- 12 kDa
- 基因ID
- 6183
- NCBI登录号
- NM_021107, NP_066930
- UniProt
- O15235
- 途径
- Sensory Perception of Sound
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