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NR1I3 抗体 (N-Term)

NR1I3 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN310698
发货至: 中国
  • 抗原 See all NR1I3 抗体
    NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
    抗原表位
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 57
    • 22
    • 19
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 豚鼠, Cow, Pig
    宿主
    • 57
    • 5
    克隆类型
    • 61
    • 3
    多克隆
    标记
    • 40
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NR1I3 antibody is un-conjugated
    应用范围
    • 50
    • 26
    • 17
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MASREDELRN CVVCGDQATG YHFNALTCEG CKGFFRRTVS KSIGPTCPFA
    预测反应
    Cow: 90%, Dog: 92%, Guinea Pig: 79%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against NR1I3. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human NR1I3
    Top Product
    Discover our top product NR1I3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 348 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
    别名
    NR1I3 (NR1I3 产品)
    别名
    AA209988 antibody, AI551208 antibody, CAR antibody, CAR-beta antibody, Care2 antibody, ESTM32 antibody, MB67 antibody, CAR1 antibody, CXR antibody, nuclear receptor subfamily 1 group I member 3 antibody, nuclear receptor subfamily 1, group I, member 3 antibody, NR1I3 antibody, Nr1i3 antibody
    背景
    NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.
    Alias Symbols: CAR, CAR1, MB67, MGC150433, MGC97144, MGC97209
    Protein Interaction Partner: HSP90AA1, RXRA, CHD9, SNX13, SNRPD3, IGH, PSMC5, PSMC4, EIF3I, SRC, MAP4, FTH1, HNF4A, NR0B2, PPARGC1A, MED1, NCOA1, POU1F1,
    Protein Size: 348
    分子量
    39 kDa
    基因ID
    9970
    NCBI登录号
    NM_005122, NP_005113
    UniProt
    Q5VTW5
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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