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MAT1A 抗体 (C-Term)

MAT1A 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN310139
发货至: 中国
  • 抗原 See all MAT1A 抗体
    MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
    抗原表位
    • 14
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 37
    • 16
    • 16
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼
    宿主
    • 36
    • 1
    克隆类型
    • 36
    • 1
    多克隆
    标记
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAT1A antibody is un-conjugated
    应用范围
    • 29
    • 18
    • 17
    • 8
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    VAKSLVKAGL CRRVLVQVSY AIGVAEPLSI SIFTYGTSQK TERELLDVVH
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against MAT1A. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human MAT1A
    Top Product
    Discover our top product MAT1A Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 395 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

  • 抗原
    MAT1A (Methionine Adenosyltransferase I, alpha (MAT1A))
    别名
    MAT1A (MAT1A 产品)
    别名
    MAT antibody, MATA1 antibody, SAMS antibody, SAMS1 antibody, AdoMet antibody, SADE antibody, SAS antibody, AI046368 antibody, Ams antibody, wu:fi35e01 antibody, zgc:55442 antibody, methionine adenosyltransferase 1A antibody, methionine adenosyltransferase I, alpha antibody, MAT1A antibody, Mat1a antibody, mat1a antibody
    背景
    MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. MAT1A is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in its gene are associated with methionine adenosyltransferase deficiency.This gne encodes methionine adenosyltransferase I (alpha isoform), which catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.
    Alias Symbols: MAT, MATA1, SAMS, SAMS1
    Protein Interaction Partner: MAT1A, UBC, IST1, MVK, MAT2A,
    Protein Size: 395
    分子量
    44 kDa
    基因ID
    4143
    NCBI登录号
    NM_000429, NP_000420
    UniProt
    Q00266
    途径
    Mitotic G1-G1/S Phases, M Phase, Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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