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HNRNPM 抗体 (N-Term)

HNRNPM 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN310054
发货至: 中国
  • 抗原 See all HNRNPM 抗体
    HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))
    抗原表位
    • 15
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 44
    • 24
    • 23
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, Pig, 犬, 马, 兔, 豚鼠
    宿主
    • 50
    • 9
    克隆类型
    • 49
    • 10
    多克隆
    标记
    • 28
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HNRNPM antibody is un-conjugated
    应用范围
    • 36
    • 28
    • 25
    • 14
    • 13
    • 13
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    ATEIKMEEES GAPGVPSGNG APGPKGEGER PAQNEKRKEK NIKRGGNRFE
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against HNRPM. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPM
    Top Product
    Discover our top product HNRNPM Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 691 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Huelga, Vu, Arnold, Liang, Liu, Yan, Donohue, Shiue, Hoon, Brenner, Ares, Yeo: "Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins." in: Cell reports, Vol. 1, Issue 2, pp. 167-78, (2012) (PubMed).

    Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原
    HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))
    别名
    HNRPM (HNRNPM 产品)
    别名
    HNRPM antibody, si:ch211-197g15.1 antibody, wu:fa10g07 antibody, wu:fa98b02 antibody, hnrpm antibody, CG9373 antibody, Dmel\\CG9373 antibody, Hrp59 antibody, cg9373 antibody, hnRNP M antibody, hrp59 antibody, p75 antibody, CEAR antibody, HNRNPM4 antibody, HNRPM4 antibody, HTGR1 antibody, NAGR1 antibody, 2610023M21Rik antibody, AA409009 antibody, Hnrpm antibody, mKIAA4193 antibody, Hnrpm4 antibody, heterogeneous nuclear ribonucleoprotein M antibody, Heterogeneous nuclear ribonucleoprotein M antibody, rumpelstiltskin antibody, HNRNPM antibody, hnrnpm antibody, hnrpm antibody, rump antibody, Hnrnpm antibody
    背景
    HNRPM belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPM has three repeats of quasi-RRM domains that bind to RNAs. HNRPM also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Multiple alternatively spliced transcript variants are known for this gene but only two transcripts has been isolated.
    Alias Symbols: DKFZp547H118, HNRNPM, HNRNPM4, HNRPM4, HTGR1, NAGR1, CEAR, HNRPM, hnRNP M
    Protein Interaction Partner: UBC, TP53, AKAP9, TEKT4, GMCL1P1, LMO2, HNRNPF, SUMO2, SUMO3, CEP250, MDM2, HAUS1, CDC37, IVNS1ABP, STAU1, SUMO1, RPA3, RPA2, RPA1, EED, rev, RTCB, RPL26L1, RFC4, PSMB8, NMT1, MRE11A, FLII, IGF2BP3, EIF2B2, EIF2B3, RPL27, RPL19, DHX9, DDX1, ABCF1, PARK2,
    Protein Size: 691
    分子量
    73 kDa
    基因ID
    4670
    NCBI登录号
    NM_031203, NP_112480
    UniProt
    P52272
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