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5mC 抗体

ABIN3071645 产品详细信息, 供应商: Log in to see
抗原
适用
人, 小鼠
宿主
小鼠
克隆类型
单克隆
应用范围
Chromatin Immunoprecipitation (ChIP)
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特异性 Recognises the C-terminal peptide of human histone H3.
纯化方法 Protein G (affinity purified)
背景 5mC (5---Methylcytosine) is a region of DNA that has been epigenetically modified through the addition of a methyl group at the 5th carbon position of cytosine. DNA methylation is a repressive histone modification that is associated with switching off gene expression. This methylation generally occurs at CpG islands and is also associated with genomic imprinting. Aberrant DNA methylation is linked to disease including many cancers.
应用备注 Chromatrap technology: 1:4 (gDNA:antibody)
Please note: Optimal antibody dilutions should be determined by the user.
限制 仅限研究用
状态 Liquid
浓度 2 mg/mL
缓冲液 Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid multiple free/thaw cycles as this may denature the antibody
储存条件 -20 °C
有效期 12 months
厂商提供的图像
Methylated DNA Immunoprecipitation (MeDIP) image for anti-5mC 抗体 (ABIN3071645) Methylated DNA Immunoprecipitation (MeDIP) assays were performed with 500ng of genomi...