Estrogen Receptor alpha 抗体 (AA 302-595)
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- 抗原 See all Estrogen Receptor alpha (ESR1) 抗体
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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抗原表位
- AA 302-595
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Estrogen Receptor alpha antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Gel Shift (GS), Inhibition Assay (InhA)
- 交叉反应
- 小鸡, Cow, 犬, Hamster, 人, 小鼠, Pig, 兔, 大鼠, 绵羊
- 产品特性
- The estrogen receptor (ER) gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
- 纯化方法
- Protein A/G Chromatography
- 免疫原
- Hybridoma produced by the fusion of splenocytes from mice immunized with the 35 kDa C-terminal fragment (aa 302-595) of human ER expressed in E. coli and mouse myeloma cells.
- 克隆位点
- TE111-5D11
- 亚型
- IgG1
- Top Product
- Discover our top product ESR1 Primary Antibody
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anti-Estrogen Receptor 1 (ESR1) (AA 129-312) antibody
ESR1 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal ESR1-3557 unconjugated
anti-Estrogen Receptor 1 (ESR1) antibodyESR1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ESR1-1904 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibodyESR1 适用: 人, 大鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6A6E8 unconjugated
anti-Estrogen Receptor 1 (ESR1) (pSer167) antibodyESR1 适用: 人, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibodyESR1 适用: 人 WB, IHC, FACS, StM 宿主: 小鼠 Monoclonal ER506 unconjugated
anti-Estrogen Receptor 1 (ESR1) (C-Term) antibodyESR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibodyESR1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB33807 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibodyESR1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (pSer118) antibodyESR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 331-360) antibodyESR1 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- This antibody can be used gel supershift assays (neat concentration), immunoprecipitation on native and denatured lysate (2 μg/mg of protein lysate), Western blotting (1-2 μg/mL) and chromatin precipitation. Can also be used to block binding of estrogen to the estrogen receptor. Optimal concentration should be evaluated by serial dilutions.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- 抗原
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- 别名
- Estrogen Receptor (ESR1 产品)
- 别名
- LOC398734 antibody, AA420328 antibody, AU041214 antibody, ER-alpha antibody, ER[a] antibody, ERa antibody, ERalpha antibody, ESR antibody, Estr antibody, Estra antibody, Nr3a1 antibody, NR3A1 antibody, eralpha antibody, zfER[a] antibody, ER antibody, ESRA antibody, ESTRR antibody, Era antibody, akap12 antibody, cb27 antibody, esr1 antibody, fb72g12 antibody, id:ibd1202 antibody, sb:cb27 antibody, si:ch73-192g21.1 antibody, wu:fb72g12 antibody, wu:fc21c03 antibody, Esr antibody, RNESTROR antibody, ERALPHA antibody, er antibody, esr antibody, nr3a1 antibody, XER antibody, era antibody, esra antibody, ERbeta antibody, xesr-1 antibody, xlERalpha1 antibody, xlERalpha2 antibody, ESR1 antibody, estrogen receptor 1 L homeolog antibody, estrogen receptor 1 (alpha) antibody, estrogen receptor 1 antibody, A kinase (PRKA) anchor protein 12b antibody, esr1.L antibody, Esr1 antibody, ESR1 antibody, esr1 antibody, akap12b antibody
- UniProt
- P11474
- 途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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