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- 抗原 See all CCR10 抗体
- CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))
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抗原表位
- AA 312-327, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CCR10 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for C-C chemokine receptor type 10(CCR10) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- FLGLRFRQDL RRLLRG
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for C-C chemokine receptor type 10(CCR10) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: chemokine(C-C motif) receptor 10
Protein Name: C-C chemokine receptor type 10(C-C CKR-10/CC-CKR-10/CCR-10) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human GPR2/CCR10(312-327aa FLGLRFRQDLRRLLRG), different from the related rat and mouse sequences by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product CCR10 Primary Antibody
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anti-Chemokine (C-C Motif) Receptor 10 (CCR10) (AA 1-52) antibody
CCR10 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 10 (CCR10) (C-Term) antibodyCCR10 适用: 人, 小鼠, 大鼠, Pig, 犬, Bat, Cow, 猴 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 10 (CCR10) (Extracellular Domain) antibodyCCR10 适用: 人, Pig, 犬, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 10 (CCR10) (AA 350-362) antibodyCCR10 适用: 人 WB, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 10 (CCR10) (C-Term) antibodyCCR10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 10 (CCR10) antibodyCCR10 适用: 人 WB, ELISA, FACS, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 10 (CCR10) antibodyCCR10 适用: 人, 小鼠, Gorilla IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 10 (CCR10) (AA 1-30) antibodyCCR10 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 10 (CCR10) (AA 312-327) antibodyCCR10 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))
- 别名
- CCR10 (CCR10 产品)
- 别名
- GPR2 antibody, Cmkbr9 antibody, Gpr2 antibody, zgc:91924 antibody, CCR10 antibody, C-C motif chemokine receptor 10 antibody, chemokine (C-C motif) receptor 10 antibody, CCR10 antibody, Ccr10 antibody, ccr10 antibody
- 背景
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CCR10, C-C chemokine receptor type 10 is a protein that in humans is encoded by the CCR10 gene. CCR10 is constitutively expressed in skin melanocytes, fibroblasts, and microvascular endothelial cells, and that it is upregulated by IL1B and TNF. Expression was also detected in T cells, Langerhans cells, and peripheral blood mononuclear cells but not in dendritic cells.By fluorescence in situ hybridization, the GPR2 gene is mapped to 17q21.1-q21.3. CCR10 is the receptor for CCL27. CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation. expression of CCL27 in normal keratinocytes and its strong upregulation in skin lesions of atopic dermatitis, contact dermatitis, and psoriasis patients. CCR10+ T lymphocytes were detected in lesional but not normal skin of these patients. Flow cytometric analysis showed that CCL27 binds extracellular matrix components and dermal microvascular endothelial cells and fibroblasts and mediates adhesion and transendothelial migration of CCR10+ circulating leukocytes. CCR10 is predominantly expressed on CD4+CLA+(cutaneous lymphocyte antigen), rather than CD8+, circulating T cells. RT-PCR, confocal microscopy, and ELISA analysis indicated that keratinocytes exposed to TNF or IL1B but not to IL4 or IFNG in vitro express increased CCL27.
Synonyms: C C chemokine receptor type 10 antibody|C C CKR 10 antibody|C-C chemokine receptor type 10 antibody|C-C CKR-10 antibody|CC chemokine receptor 10 antibody|CC CKR 10 antibody|CC-CKR-10 antibody|CCR 10 antibody|CCR-10 antibody|CCR10 antibody|CCR10_HUMAN antibody|Chemokine(C C motif) receptor 10 antibody|G protein coupled receptor 2 antibody|G protein-coupled receptor 2 antibody|G-protein coupled receptor 2 antibody|GPR 2 antibody|GPR2 antibody - UniProt
- P46092
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