Aromatase 抗体 (C-Term)
(4 references)-
- 抗原 See all Aromatase (CYP19A1) 抗体
- Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))
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抗原表位
- AA 485-503, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aromatase antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Aromatase(CYP19A1) detection. Tested with WB, IHC-P in Human.
- 序列
- KNMLEMIFTP RNSDRCLEH
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Aromatase(CYP19A1) detection. Tested with WB, IHC-P in Human.
Gene Name: cytochrome P450, family 19, subfamily A, polypeptide 1
Protein Name: Aromatase - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Aromatase(485-503aa KNMLEMIFTPRNSDRCLEH).
- 亚型
- IgG
- Top Product
- Discover our top product CYP19A1 Primary Antibody
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anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (AA 41-140) antibody
CYP19A1 适用: 人, 大鼠, 小鼠, Cow WB, ELISA, IHC (p), ICC, FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (AA 1-180) antibodyCYP19A1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) antibodyCYP19A1 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) antibodyCYP19A1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 1H1 unconjugated Recombinant Antibody
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) antibodyCYP19A1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (AA 453-485), (C-Term) antibodyCYP19A1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14708 unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (AA 51-150) antibodyCYP19A1 适用: 人, 小鼠, 绵羊 WB, ELISA, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (Internal Region) antibodyCYP19A1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (AA 1-503) antibodyCYP19A1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) (Internal Region) antibodyVerified CYP19A1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "MiRNA-143 mediates the proliferative signaling pathway of FSH and regulates estradiol production." in: The Journal of endocrinology, Vol. 234, Issue 1, pp. 1-14, (2017) (PubMed).
: "Estradiol synthesis and release in cultured female rat bone marrow stem cells." in: BioMed research international, Vol. 2013, pp. 301540, (2013) (PubMed).
: "Extragonadal aromatization increases with time after ovariectomy in rats." in: Reproductive biology and endocrinology : RB&E, Vol. 3, pp. 6, (2006) (PubMed).
: "Electroacupuncture stimulates hypothalamic aromatization." in: Brain research, Vol. 1037, Issue 1-2, pp. 164-70, (2005) (PubMed).
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: "MiRNA-143 mediates the proliferative signaling pathway of FSH and regulates estradiol production." in: The Journal of endocrinology, Vol. 234, Issue 1, pp. 1-14, (2017) (PubMed).
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- 抗原
- Aromatase (CYP19A1) (Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1))
- 别名
- CYP19A1 (CYP19A1 产品)
- 别名
- ARO antibody, ARO1 antibody, CPV1 antibody, CYAR antibody, CYP19 antibody, CYPXIX antibody, P-450AROM antibody, Aromatase antibody, Cyp19 antibody, Cyp19a antibody, p450arom antibody, P450 arom antibody, aro antibody, cyp19 antibody, cyp19a antibody, p450arom-A antibody, P450AROM antibody, Ar antibody, ArKO antibody, Int-5 antibody, Int5 antibody, CYP19P1 antibody, CYP19A1 antibody, CYP19a1 antibody, P450aromA antibody, ar1 antibody, cypXIX antibody, etID309862.18 antibody, zgc:136541 antibody, AroB antibody, CYP19a2 antibody, P450aromB antibody, cyp19b antibody, zgc:92614 antibody, cyp19a1 antibody, cytochrome P450 family 19 subfamily A member 1 antibody, cytochrome P450, family 19, subfamily a, polypeptide 1 antibody, cytochrome P450 family 19 subfamily A member 1 L homeolog antibody, aromatase antibody, cytochrome P450 aromatase antibody, cytochrome P450, family 19, subfamily A, polypeptide 1 antibody, cytochrome P450 19A1 antibody, cytochrome P450, family 17, subfamily A, polypeptide 1 antibody, cytochrome P450, family 19 antibody, cytochrome P450, family 19, subfamily A, polypeptide 1a antibody, cytochrome P450, family 19, subfamily A, polypeptide 1b antibody, cytochrome P450 19A1-like antibody, CYP19A1 antibody, Cyp19a1 antibody, cyp19a1.L antibody, SAV_2383 antibody, pfcyp19b-tstr antibody, CYP19 antibody, cyp19a1a antibody, cyp19a1b antibody, LOC101174651 antibody
- 背景
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Aromatase is an enzyme responsible for a key step in the biosynthesis of estrogens. It is a member of the cytochrome P450 superfamily, which are monooxygenases that catalyze many reactions involved in steroidogenesis. In particular, aromatase is responsible for the aromatization of androgens into estrogens. The CYP19 gene spans at least 70 kb of genomic DNA and contains 10 exons. By in situ hybridization, the ARO gene is mapped to 15q21.1. The aromatase enzyme can be found in many tissues including gonads, brain, adipose tissue, placenta, blood vessels, skin, bone, and endometrium, as well as in tissue of endometriosis, uterine fibroids, breast cancer, and endometrial cancer. It is an important factor in sexual development. Some bodybuilders taking steroids also take antiaromatase supplements to prevent excess testosterone conversion into estrogens, which can cause gynecomastia.
Synonyms: ARO 1 antibody|ARO antibody|ARO1 antibody|Aromatase antibody|CP19A_HUMAN antibody|CPV antibody|CPV1 antibody|CYAR antibody|CYP19 antibody|CYP19A1 antibody|CYPXIX antibody|Cytochrome P-450AROM antibody|Cytochrome P450 19A1 antibody|Cytochrome P450 family 19 subfamily A polypeptide 1 antibody|Cytochrome P450, family 19, subfamily A, polypeptide 1 antibody|Cytochrome P450, subfamily XIX(aromatization of androgens) antibody|Estrogen synthase antibody|Estrogen synthetase antibody|Flavoprotein linked monooxygenase antibody|MGC104309 antibody|Microsomal monooxygenase antibody|OTTHUMP00000162543 antibody|OTTHUMP00000198350 antibody|P 450AROM antibody|P450AROM antibody - UniProt
- P11511
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis
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