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IGF1 抗体 (Middle Region)

Name: IGF1 抗体 (Middle Region)
SKU: ABIN3044390
Availability: OutOfStock

IGF1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Anti-IGF1 antibody, Western blotting WB: Recombinant Human IGF-1 Protein 2.

Anti-IGF1 antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue

IHC

2 images

(6 references)

产品编号 ABIN3044390

发货至: 中国

Datasheet as PDF

抗原 See all IGF1 抗体

IGF1 (Insulin-Like Growth Factor 1 (IGF1))
抗原表位
18

15

15

9

8

4

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 80-96, Middle Region
适用
150

68

60

22

16

9

7

3

2

1
人, 大鼠
宿主
128

50

10

2

1

1
兔
Compatible Secondaries
克隆类型
137

53
多克隆
标记
94

29

13

7

5

5

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This IGF1 antibody is un-conjugated
应用范围
144

77

66

57

42

30

27

26

26

20

15

13

9

8

8

7

7

6

4

2

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Insulin-like growth factor I(IGF1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

序列

GSSSRRAPQT GIVDECC

交叉反应（详细）

Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

产品特性

Rabbit IgG polyclonal antibody for Insulin-like growth factor I(IGF1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: insulin-like growth factor 1(somatomedin C)
Protein Name: Insulin-like growth factor I(IGF-I)

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human IGF-1(80-96 aa GSSSRRAPQTGIVDECC), different from the mouse and rat sequences by one amino acid.

亚型

IgG

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anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) antibody
IGF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-153) antibody
IGF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (Internal Region) antibody
Verified IGF1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 115-144) antibody
IGF1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 49-100) antibody
IGF1 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, IP, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 33-102) antibody
IGF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) antibody
IGF1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) (AA 115-144), (C-Term) antibody
IGF1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB33711 unconjugated

anti-Insulin-Like Growth Factor 1 (IGF1) antibody (HRP)
IGF1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

有效期

12 months
Wan, Wang, Xiong, Xiang, Li, Wang, Liu, Niu, Peng, Jiang, Chai: "Elucidating a molecular mechanism that the deterioration of porcine meat quality responds to increased cortisol based on transcriptome sequencing." in: Scientific reports, Vol. 6, pp. 36589, (2018) (PubMed).

Li, Zhang, Li, Zhao, Zhai, Yang, Kong, Wu, Chen, Teng: "miR-18a counteracts AKT and ERK activation to inhibit the proliferation of pancreatic progenitor cells." in: Scientific reports, Vol. 7, pp. 45002, (2017) (PubMed).

Huang, Zhou, Shi, Shao, Wang, Wang, Wang, Ding: "Effects of the IGF-1/PTEN/Akt/FoxO signaling pathway on male reproduction in rats subjected to water immersion and restraint stress." in: Molecular medicine reports, Vol. 14, Issue 6, pp. 5116-5124, (2017) (PubMed).

Tang, Liao, Xu, Zhang, Liu, Deng, Jiang, Fu, Chen, Zhou: "Estrogen and insulin-like growth factor 1 synergistically promote the development of lung adenocarcinoma in mice." in: International journal of cancer. Journal international du cancer, Vol. 133, Issue 10, pp. 2473-82, (2013) (PubMed).

Huang, Zhou, Wang, Wei, Zhang, Zhou, Hutz, Shi: "Effect of the IGF-1/PTEN/Akt/FoxO signaling pathway on the development and healing of water immersion and restraint stress-induced gastric ulcers in rats." in: International journal of molecular medicine, Vol. 30, Issue 3, pp. 650-8, (2012) (PubMed).

Chai, Guo, Wang, Fu, Guan, Tan, Ren, Yang: "Antibacterial effect of 317L stainless steel contained copper in prevention of implant-related infection in vitro and in vivo." in: Journal of materials science. Materials in medicine, Vol. 22, Issue 11, pp. 2525-35, (2011) (PubMed).
抗原

IGF1 (Insulin-Like Growth Factor 1 (IGF1))

别名

IGF1 (IGF1 产品)

别名

IGF-I antibody, IGF1A antibody, IGFI antibody, C730016P09Rik antibody, Igf-1 antibody, Igf-I antibody, Npt2B antibody, IGF-1 antibody, IGFIA antibody, IGF-IB antibody, igf1 antibody, IGF-1L antibody, IGF-1a antibody, IGF1 antibody, igf-1 antibody, igf1-A antibody, igf1.S antibody, xigf1 antibody, insulin like growth factor 1 antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I antibody, insulin like growth factor 1 L homeolog antibody, IGF1 antibody, Igf1 antibody, LOC100136741 antibody, igf1 antibody, LOC678666 antibody, igf1.L antibody, LOC104911603 antibody

背景

Insulin-like growth factor 1(IGF-1) also known as somatomedin C or mechano growth factor is a protein that in humans is encoded by the IGF1 gene. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons.Justice et al.(1990) placed the mouse IGF1 gene on chromosome 10.

Synonyms: IBP1 antibody|IGF 1 antibody|IGF I antibody|IGF IA antibody|IGF IB antibody|IGF-I antibody|Igf1 antibody|IGF1_HUMAN antibody|IGFI antibody|IGFIA antibody|Insulin like growth factor 1(somatomedin C) antibody|Insulin like growth factor 1 antibody|Insulin like growth factor IA antibody|Insulin like growth factor IB antibody|Insulin-like growth factor I antibody|Mechano growth factor antibody|MGF antibody|OTTHUMP00000195080 antibody|OTTHUMP00000195081 antibody|OTTHUMP00000195082 antibody|OTTHUMP00000195083 antibody|OTTHUMP00000195084 antibody|Somatomedia C antibody|Somatomedin C antibody|Somatomedin-C antibody

UniProt

P05019

途径

RTK signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation