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TRAF2 抗体 (Middle Region)

TRAF2 适用: 人, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044047
发货至: 中国
  • 抗原 See all TRAF2 抗体
    TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))
    抗原表位
    • 16
    • 8
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    • 2
    • 1
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    AA 305-325, Middle Region
    适用
    • 94
    • 29
    • 27
    • 1
    • 1
    人, 大鼠
    宿主
    • 77
    • 17
    • 1
    • 1
    克隆类型
    • 68
    • 28
    多克隆
    标记
    • 43
    • 7
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    • 4
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    • 3
    • 1
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    This TRAF2 antibody is un-conjugated
    应用范围
    • 70
    • 34
    • 22
    • 22
    • 17
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    • 11
    • 9
    • 3
    • 3
    • 2
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    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    原理
    Rabbit IgG polyclonal antibody for TNF receptor-associated factor 2(TRAF2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    序列
    RQHRLDQDKI EALSSKVQQL E
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for TNF receptor-associated factor 2(TRAF2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Gene Name: TNF receptor-associated factor 2
    Protein Name: TNF receptor-associated factor 2
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human TRAF2(305-325aa RQHRLDQDKIEALSSKVQQLE), different from the related rat and mouse sequences by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product TRAF2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for TRAF2 is approximately 1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))
    别名
    TRAF2 (TRAF2 产品)
    别名
    MGC:45012 antibody, TRAP antibody, TRAP3 antibody, TANK antibody, AI325259 antibody, TNF-receptor-associated factor 2 antibody, conjugal transfer protein TraF antibody, TNF receptor associated factor 2 antibody, TNF receptor-associated factor 2 antibody, Tnf receptor-associated factor 2 antibody, LOC661716 antibody, traF2 antibody, TRAF2 antibody, Traf2 antibody
    背景
    TRAF2(TNF Receptor-Associated Factor 2), also called TRAP, is a protein that in humans is encoded by the TRAF2 gene. The protein encoded by this gene is a member of the TNF receptor(TNFR) associated factor(TRAF) protein family. TRAF2 is a common signal transducer for TNFR2 and CD40 that mediates activation of NF-kappa-B. Rothe et al.(1996) identified ITRAF, which binds to TRAF1, TRAF2, and TRAF3, and that when overexpressed inhibits TRAF2-mediated NF-kappa-B activation. They proposed that ITRAF is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in a latent state in the cytoplasm. Kanamori et al.(2002) found that mouse Traf2 interacted directly with T2bp, and they presented evidence that T2BP is involved in TNF-mediated signaling by its interaction with TRAF2.

    Synonyms: E3 ubiquitin-protein ligase TRAF2 antibody|MGC: 45012 antibody|OTTHUMP00000022625 antibody|OTTHUMP00000064745 antibody|TNF receptor associated factor 2 antibody|TNF receptor-associated factor 2 antibody|TNF receptor-associated protein antibody|TRAF 2 antibody|TRAF2 antibody|TRAF2_HUMAN antibody|TRAP 3 antibody|TRAP antibody|TRAP3 antibody|Tumor necrosis factor type 2 receptor associated protein 3 antibody|Tumor necrosis factor type 2 receptor-associated protein 3 antibody
    UniProt
    Q12933
    途径
    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response, S100 Proteins
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