MAD2L1 抗体 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (AA 2-205)

Details for Product anti-MAD2L1 Antibody No. ABIN3043608, 供应商: Log in to see
抗原
  • cb408
  • zgc:112133
  • MAD2L1
  • mad2
  • XMad2
  • AA673185
  • MAD2
  • HSMAD2
  • MAD2 mitotic arrest deficient-like 1 (yeast)
  • MAD2 mitotic arrest deficient-like 1
  • MAD2L1
  • mad2l1
  • LOC100218172
  • Mad2l1
抗原表位
AA 2-205
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适用

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宿主

71
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克隆类型
多克隆
标记
This MAD2L1 antibody is un-conjugated
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应用范围
Western Blotting (WB)
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原理 Rabbit IgG polyclonal antibody for Mitotic spindle assembly checkpoint protein MAD2A(MAD2L1) detection. Tested with WB in Human.
免疫原 E.coli-derived human Mad2L1 recombinant protein (Position: A2-D205). Human Mad2L1 shares 94% amino acid (aa) sequence identity with mouse Mad2L1.
亚型 IgG
交叉反应 (详细) No cross reactivity with other proteins.
产品特性 Rabbit IgG polyclonal antibody for Mitotic spindle assembly checkpoint protein MAD2A(MAD2L1) detection. Tested with WB in Human.
Gene Name: MAD2 mitotic arrest deficient-like 1 (yeast)
Protein Name: Mitotic spindle assembly checkpoint protein MAD2A
纯化方法 Immunogen affinity purified.
别名 MAD2L1 (MAD2L1 Antibody 摘要)
背景 Mitotic spindle assembly checkpoint protein MAD2A is a protein that in humans is encoded by the MAD2L1 gene. This gene belongs to the MAD2 family. It is mapped to 4q27. MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The protein has two highly different native conformations, an inactive open conformation that cannot bind CDC20 and that predominates in cytosolic monomers, and an active closed conformation. It is required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment.

Synonyms: Homolog of MAD2 S cerevisiae antibody|HsMAD 2 antibody|HsMAD2 antibody|Human mitotic feedback control protein Madp2 antibody|MAD 2 antibody|MAD 2A antibody|MAD2 antibody|MAD2 like 1 antibody|MAD2 like protein 1 antibody|MAD2 mitotic arrest deficient like 1 antibody|MAD2-like protein 1 antibody|MAD2A antibody|Mad2l1 antibody|MD2L1_HUMAN antibody|Mitotic arrest deficient 2-like protein 1 antibody|Mitotic arrest deficient like 1 antibody|Mitotic arrest deficient yeast homolog antibody|Mitotic arrest deficient yeast homolog like 1 antibody|Mitotic spindle assembly checkpoint protein antibody|Mitotic spindle assembly checkpoint protein MAD2A antibody
基因ID 4085
UniProt Q13257
研究领域 Cell Cycle
应用备注 WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Mad2L1 is approximately 0.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.
说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制 仅限研究用
状态 Lyophilized
溶解方式 Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
浓度 500 μg/mL
缓冲液 Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
厂商提供的图像
Western Blotting (WB) image for anti-MAD2L1 抗体 (MAD2 Mitotic Arrest Deficient-Like 1 (Yeast)) (AA 2-205) (ABIN3043608) Anti- Mad2L1 Picoband antibody, Western blotting All lanes: Anti Mad2L1 at 0.5ug/ml ...