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L-Selectin 抗体 (AA 39-372)

SELL 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043326
发货至: 中国
  • 抗原 See all L-Selectin (SELL) 抗体
    L-Selectin (SELL) (Selectin L (SELL))
    抗原表位
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    AA 39-372
    适用
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    宿主
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    克隆类型
    • 130
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    多克隆
    标记
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    This L-Selectin antibody is un-conjugated
    应用范围
    • 135
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    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for L-selectin(SELL) detection. Tested with WB, IHC-P, ELISA in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for L-selectin(SELL) detection. Tested with WB, IHC-P, ELISA in Human,Mouse,Rat.
    Gene Name: selectin L
    Protein Name: L-selectin
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived human L-selectin recombinant protein (Position: W39-Y372). Human L-selectin shares 77.5 % and 78.7 % amino acid (aa) sequence identity with mouse and rat L-selectin, respectively.
    亚型
    IgG
    Top Product
    Discover our top product SELL Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat , The detection limit for L-selectin is approximately 0.1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    L-Selectin (SELL) (Selectin L (SELL))
    别名
    SELL (SELL 产品)
    别名
    CD62L antibody, LAM1 antibody, LECAM1 antibody, LEU8 antibody, LNHR antibody, LSEL antibody, LYAM1 antibody, PLNHR antibody, TQ1 antibody, A.11 antibody, L-selectin antibody, LECAM-1 antibody, SELE antibody, AI528707 antibody, Lnhr antibody, Ly-22 antibody, Ly-m22 antibody, Lyam-1 antibody, Lyam1 antibody, selectin L antibody, selectin, lymphocyte antibody, SELL antibody, Sell antibody
    物质类
    Chemical
    背景
    CD62L, also known as L-selectin, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.

    Synonyms: A.11 antibody|AI528707 antibody|CD62 antigen ligand antibody|CD62 antigen-like family member L antibody|CD62L antibody|gp90 MEL antibody|gp90-MEL antibody|hLHRc antibody|IgA nephropathy, susceptibility to, included antibody|L Selectin antibody|L-selectin antibody|LAM-1 antibody|LAM1 antibody|LECAM1 antibody|LEU8 antibody|Leukocyte adhesion molecule 1 antibody|Leukocyte surface antigen Leu-8 antibody|Leukocyte surface antigen Leu8 antibody|Leukocyte-endothelial cell adhesion molecule 1 antibody|LNHR antibody|LSEL antibody|Ly-22 antibody|Ly-m22 antibody|Lyam-1 antibody|LYAM1 antibody|LYAM1_HUMAN antibody|Lymph node homing receptor antibody|Lymphocyte adhesion molecule 1 antibody|Lymphocyte antigen 22 antibody|Lymphocyte surface MEL-14 antigen antibody|MEL-14 antibody|Pln homing receptor antibody|PLNHR antibody|Selectin L antibody|Selectin, lymphocyte antibody|SELL antibody|TQ1 antibody
    基因ID
    6402
    UniProt
    P14151
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