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Cytokeratin 19 抗体 (C-Term)

Name: Cytokeratin 19 抗体 (C-Term)
SKU: ABIN3043288
Availability: OutOfStock

KRT19 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Keratin 19 (KRT19) (AA 334-372), (C-Term) antibody (ABIN3043288)

IHC (p)

4 images

(5 references)

产品编号 ABIN3043288

发货至: 中国

Datasheet as PDF

抗原 See all Cytokeratin 19 (KRT19) 抗体

Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
抗原表位
21

16

16

10

8

7

6

5

5

5

5

5

4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 334-372, C-Term
适用
261

90

72

8

7

7

5

5

4

2

2

2

2

2

2

1

1

1

1

1
人, 小鼠, 大鼠
宿主
138

132

3

2

1
兔
Compatible Secondaries
克隆类型
144

132
多克隆
标记
124

33

20

13

7

5

5

5

5

5

5

5

4

4

4

4

4

4

3

3

3

3

3

2

2

1

1
This Cytokeratin 19 antibody is un-conjugated
应用范围
192

95

87

81

69

48

40

39

33

31

24

23

7

6

6

5

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Keratin, type I cytoskeletal 19(KRT19) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

序列

QLAHIQALIS GIEAQLGDVR ADSERQNQEY QRLMDIKSR

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Keratin, type I cytoskeletal 19(KRT19) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: keratin 19
Protein Name: Keratin, type I cytoskeletal 19

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Cytokeratin 19 (334-372aa QLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSR), different from the related mouse and rat sequences by nine amino acids.

亚型

IgG

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KRT19 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

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KRT19 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8H1A8 unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Quan, Du, Hou, Wang, Zhang: "Utilization of E-cadherin by monocytes from tumour cells plays key roles in the progression of bone invasion by oral squamous cell carcinoma." in: Oncology reports, Vol. 38, Issue 2, pp. 850-858, (2017) (PubMed).

Jeng, Jeng, Jeng, Sheen, Li, Lu, Chang: "Tropism of liver epithelial cells toward hepatocellular carcinoma in vitro and in vivo with altering gene expression of cancer stem cells." in: American journal of surgery, Vol. 215, Issue 4, pp. 735-743, (2017) (PubMed).

Li, Zhang, Zhang, Liu, Qi, Zhao, Jiang, Zhai, Ji, Luo: "Stem cell-like circulating tumor cells indicate poor prognosis in gastric cancer." in: BioMed research international, Vol. 2014, pp. 981261, (2015) (PubMed).

Yin, Tian, Ye, Li, Wang, Cheng, Chen, Guo, Huang: "Nanog and ?-catenin: a new convergence point in EpSC proliferation and differentiation." in: International journal of molecular medicine, Vol. 29, Issue 4, pp. 587-92, (2012) (PubMed).

Lu, Gu, Xu, Liu, Xie, Song: "Adult islets cultured in collagen gel transdifferentiate into duct-like cells." in: World journal of gastroenterology, Vol. 11, Issue 22, pp. 3426-30, (2005) (PubMed).
抗原

Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

别名

KRT19 (KRT19 产品)

别名

CK19 antibody, K19 antibody, K1CS antibody, AI663979 antibody, EndoC antibody, Krt-1.19 antibody, Krt1-19 antibody, Ka19 antibody, k19 antibody, ck19 antibody, k1cs antibody, krt9 antibody, krt15 antibody, MGC76282 antibody, GK-19 antibody, MGC83069 antibody, KRT19 antibody, keratin 19 antibody, keratin 19 L homeolog antibody, keratin, type I cytoskeletal 19 antibody, KRT19 antibody, Krt19 antibody, krt19 antibody, krt19.L antibody, LOC100344434 antibody, LOC101117946 antibody

背景

Keratin, type I cytoskeletal 19 is a protein that in humans is encoded by the KRT19 gene. The protein encoded by this gene is a member of the keratin family. It is specifically expressed in the periderm, the transiently superficial layer that envelops the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.

Synonyms: 40 kDa keratin intermediate filament antibody|CK 19 antibody|CK-19 antibody|ck19 antibody| Cytokeratin 19 antibody|Cytokeratin-19 antibody|k19 antibody|K1C19_HUMAN antibody|k1cs antibody|Keratin 19 antibody|Keratin type I 40 kD antibody|Keratin type i 40kD antibody| Keratin type I cytoskeletal 19 antibody|Keratin, type I cytoskeletal 19 antibody|Keratin, type I, 40 kd antibody|Keratin-19 antibody|krt19 antibody|mgc15366 antibody

基因ID

3880

UniProt

P08727