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Desmin 抗体 (AA 1-304)

DES 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043265
发货至: 中国
  • 抗原 See all Desmin (DES) 抗体
    Desmin (DES)
    抗原表位
    • 17
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    • 1
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    • 1
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    AA 1-304
    适用
    • 149
    • 79
    • 77
    • 33
    • 18
    • 11
    • 11
    • 8
    • 8
    • 5
    • 4
    • 3
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 111
    • 37
    • 2
    克隆类型
    • 105
    • 46
    多克隆
    标记
    • 76
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
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    • 3
    • 3
    • 3
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    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Desmin antibody is un-conjugated
    应用范围
    • 115
    • 69
    • 55
    • 44
    • 27
    • 22
    • 14
    • 13
    • 10
    • 8
    • 6
    • 3
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    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    原理
    Rabbit IgG polyclonal antibody for Desmin(DES) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Desmin(DES) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
    Gene Name: desmin
    Protein Name: Desmin
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human Desmin recombinant protein (Position: M1-T304). Human Desmin shares 97% amino acid (aa) sequences identity with both mouse and rat Desmin.
    亚型
    IgG
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Desmin is approximately 0.25 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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    Liu, Du, Zhu, Zhang, Sun, Liu, Li, Wang, Du: "Identification of apoptosis-related microRNAs and their target genes in myocardial infarction post-transplantation with skeletal myoblasts." in: Journal of translational medicine, Vol. 13, pp. 270, (2016) (PubMed).

    Jiang, Zhang, Fang, Zhang, Lu, Zhu, Cheng, Ai, Zhou, Li, Fang, Yao: "Analgesic effects of Chinese Tuina massage in a rat model of pain." in: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1367-1374, (2016) (PubMed).

    Zhang, Deng, Wen, Chen, Liu, Ye, Huang, Jiang, Xiong: "PPAR? and MyoD are differentially regulated by myostatin in adipose-derived stem cells and muscle satellite cells." in: Biochemical and biophysical research communications, Vol. 458, Issue 2, pp. 375-80, (2015) (PubMed).

    Gao, Zhi, Yang, Li, Yan, Wang: "Low dose of IGF-I increases cell size of skeletal muscle satellite cells via Akt/S6K signaling pathway." in: Journal of cellular biochemistry, Vol. 116, Issue 11, pp. 2637-48, (2015) (PubMed).

    Sondag, Salihoglu, Lababidi, Crowder, Moussa, Abdelmagid, Safadi: "Osteoactivin induces transdifferentiation of C2C12 myoblasts into osteoblasts." in: Journal of cellular physiology, Vol. 229, Issue 7, pp. 955-66, (2014) (PubMed).

    Wei, Yang, Wang, Xu, Liang, Zhou: "Sodium ferulate lowers portal pressure in rats with secondary biliary cirrhosis through the RhoA/Rho-kinase signaling pathway: a preliminary study." in: International journal of molecular medicine, Vol. 34, Issue 5, pp. 1257-67, (2014) (PubMed).

    Pan, Chen, Huang, Yao, Ma: "Transforming growth factor ?1 induces the expression of collagen type I by DNA methylation in cardiac fibroblasts." in: PLoS ONE, Vol. 8, Issue 4, pp. e60335, (2013) (PubMed).

    Wu, Gu, Zhao, Tan, Chen, Zhu, Zhang: "Derivation of multipotent nestin(+)/CD271 (-)/STRO-1 (-) mesenchymal-like precursors from human embryonic stem cells in chemically defined conditions." in: Human cell, Vol. 26, Issue 1, pp. 19-27, (2013) (PubMed).

    Liu, Liu, Xu, Wang, Zhu, Li, Wang, Liu, Ma, Wu: "Neurotransmitter noradrenaline downregulate cytoskeletal protein expression of VSMCs." in: Experimental and molecular pathology, Vol. 94, Issue 1, pp. 79-83, (2013) (PubMed).

    Yan, Gan, Yang, Sun: "The proliferation and differentiation characteristics of co-cultured porcine preadipocytes and muscle satellite cells in vitro." in: Molecular biology reports, Vol. 40, Issue 4, pp. 3197-202, (2013) (PubMed).

    Liu, Wang, Du, Liu, Liu, Zhang, Zhang, Hou, Liu, Zhang, Yu: "Wnt1 inhibits hydrogen peroxide-induced apoptosis in mouse cardiac stem cells." in: PLoS ONE, Vol. 8, Issue 3, pp. e58883, (2013) (PubMed).

    Qian, Qian, Zhang, Zhu, Yan, Ye, Peng, Li, Xu, Sun, Xu: "5-Azacytidine induces cardiac differentiation of human umbilical cord-derived mesenchymal stem cells by activating extracellular regulated kinase." in: Stem cells and development, Vol. 21, Issue 1, pp. 67-75, (2012) (PubMed).

    Liu, Wang, Yu, Zhang, Chen, Jin, Dai, Li, Xu: "Injection of duck recombinant follistatin fusion protein into duck muscle tissues stimulates satellite cell proliferation and muscle fiber hypertrophy." in: Applied microbiology and biotechnology, Vol. 94, Issue 5, pp. 1255-63, (2012) (PubMed).

    Wang, Yang, Yang, Shu, Wang, Jiang, Yuan, Wu: "The differential proliferative ability of satellite cells in Lantang and Landrace pigs." in: PLoS ONE, Vol. 7, Issue 3, pp. e32537, (2012) (PubMed).

    Zhang, Zheng, Yu, Min, Yu, Ye, Xie, Zhang: "Lentiviral vector-mediated down-regulation of IL-17A receptor in hepatic stellate cells results in decreased secretion of IL-6." in: World journal of gastroenterology, Vol. 18, Issue 28, pp. 3696-704, (2012) (PubMed).

    Longxi, Buwu, Yuan, Sinan: "Expression of p53 in the effects of artesunate on induction of apoptosis and inhibition of proliferation in rat primary hepatic stellate cells." in: PLoS ONE, Vol. 6, Issue 10, pp. e26500, (2011) (PubMed).

    Liu, Li, Chen, Cao, Zhang, Yu, Xu, He, Wang: "Characterization of in vitro cultured myoblasts isolated from duck (Anas platyrhynchos) embryo." in: Cytotechnology, Vol. 63, Issue 4, pp. 399-406, (2011) (PubMed).

    Xu, Qian, Zhu, Zhang, Yan, Wang, Xu: "Isolation of cancer stem cells from transformed human mesenchymal stem cell line F6." in: Journal of molecular medicine (Berlin, Germany), Vol. 88, Issue 11, pp. 1181-90, (2010) (PubMed).

    Wang, Fan, Zhang, Liu, Sun, Wang: "Compatibility of hyaluronic acid hydrogel and skeletal muscle myoblasts." in: Biomedical materials (Bristol, England), Vol. 4, Issue 2, pp. 25011, (2009) (PubMed).

  • 抗原
    Desmin (DES)
    别名
    DES (DES 产品)
    别名
    DES antibody, des-b antibody, MGC80853 antibody, des antibody, csm1 antibody, csm2 antibody, desm antibody, cmd1i antibody, MGC75911 antibody, LOC100220724 antibody, desmin antibody, cb290 antibody, fb59a12 antibody, wu:fb59a12 antibody, zgc:109859 antibody, CSM1 antibody, CSM2 antibody, LGMD2R antibody, wu:fc11d08 antibody, zgc:154009 antibody, des-a antibody, MGC52614 antibody, desmin antibody, desmin, gene 1 L homeolog antibody, desmin, gene 1 antibody, desmin a antibody, desmin b antibody, desmin, gene 1 S homeolog antibody, desmin, gene 2 S homeolog antibody, DES antibody, des.1.L antibody, des.1 antibody, des antibody, desma antibody, Des antibody, desmb antibody, des.1.S antibody, des.2.S antibody
    背景
    DES, also called desmin, is a protein that in humans is encoded by the DES gene, and this gene is mapped to 2q35. DES is the muscle-specific member of the intermediate filament (IF) protein family. It is one of the earliest myogenic markers, both in heart and somites, and is expressed in satellite stem cells and replicating myoblasts. DES is very important in muscle cell architecture and structure since it connects many components of the cytoplasm. It may be also play an important role in mitochondria function. What's more, DES provides attachments between the terminal Z disc and membrane-associated proteins to form a force-transmitting system that parallels the thin filaments at myotendinous junctions.

    Synonyms: CMD1I antibody|CSM1 antibody|CSM2 antibody|DES antibody|DESM_HUMAN antibody|Desmin antibody|FLJ12025 antibody|FLJ39719 antibody|FLJ41013 antibody|FLJ41793 antibody|Intermediate filament protein antibody|OTTHUMP00000064865 antibody
    基因ID
    1674
    UniProt
    P17661
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