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IL-31 抗体 (Center)

IL31 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN303271
发货至: 中国
  • 抗原 See all IL-31 (IL31) 抗体
    IL-31 (IL31) (Interleukin 31 (IL31))
    抗原表位
    • 15
    • 13
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 57
    • 9
    • 9
    人, 小鼠
    宿主
    • 52
    • 18
    克隆类型
    • 52
    • 18
    多克隆
    标记
    • 32
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-31 antibody is un-conjugated
    应用范围
    • 38
    • 30
    • 22
    • 14
    • 14
    • 14
    • 10
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody reacts with Interleukin 31 (IL31).
    纯化方法
    Affinity Chromatography.
    免疫原
    Synthetic Peptide corresponding to 18 amino acid peptide from near the center of human IL-31.
    Top Product
    Discover our top product IL31 Primary Antibody
  • 应用备注
    Immunohistochemistry on Paraffin Sections (5 μg/mL). Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.
  • 抗原
    IL-31 (IL31) (Interleukin 31 (IL31))
    别名
    Interleukin-31 / IL31 (IL31 产品)
    别名
    IL-31 antibody, 1700013B14Rik antibody, IL31 antibody, interleukin 31 antibody, IL31 antibody, Il31 antibody
    背景
    Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia and skin lesions, and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.Synonyms: IL-31
    基因ID
    386653
    NCBI登录号
    NP_001014358
    UniProt
    Q6EBC2
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