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DBNL 抗体 (N-Term)

DBNL 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856301
发货至: 中国
  • 抗原 See all DBNL 抗体
    DBNL (Drebrin-Like (DBNL))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 23
    • 19
    • 2
    • 2
    • 1
    • 1
    宿主
    • 35
    • 2
    • 1
    克隆类型
    • 36
    • 2
    多克隆
    标记
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DBNL antibody is un-conjugated
    应用范围
    • 36
    • 18
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    小鼠, 大鼠, 牛
    交叉反应 (详细)
    Mouse (92 %), Rat (92 %), Bovine (84 %)
    产品特性
    Rabbit Polyclonal antibody to HIP55 (drebrin-like)
    HIP55 antibody [N1], N-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HIP55. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: HeLaS3 , Molt-4

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    DBNL (Drebrin-Like (DBNL))
    别名
    HIP55 (DBNL 产品)
    别名
    ABP1 antibody, HIP-55 antibody, HIP55 antibody, SH3P7 antibody, Abp1 antibody, mAbp1 antibody, Sh3p7 antibody, abp1 antibody, dbnl-B antibody, DBNL antibody, DKFZp459C0939 antibody, drebrin like antibody, drebrin-like antibody, drebrin like S homeolog antibody, drebrin 1 antibody, DBNL antibody, Dbnl antibody, dbnl.S antibody, LOC100148204 antibody, DBN1 antibody
    背景
    Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.

    Cellular Localization: Cytoplasm , cytoskeleton , Cell projection , lamellipodium
    分子量
    48 kDa
    基因ID
    28988
    途径
    TCR Signaling, Regulation of Actin Filament Polymerization
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