MAPK8IP1 抗体 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1) (Center)

Details for Product anti-MAPK8IP1 Antibody No. ABIN2854806, 供应商: Log in to see
抗原
  • IB1
  • JIP-1
  • Jip1
  • Prkm8ip
  • Skip
  • mjip-2a
  • JIP1
  • Jip-1
  • Mapk8ip
  • PRKM8IP
  • mitogen-activated protein kinase 8 interacting protein 1
  • MAPK8IP1
  • LOC100344706
  • Mapk8ip1
抗原表位
Center
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适用
人, 小鼠
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宿主

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克隆类型
多克隆
标记
This MAPK8IP1 antibody is un-conjugated
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应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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选项
Supplier
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Supplier Product No.
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免疫原 Recombinant protein encompassing a sequence within the center region of human JIP1. The exact sequence is proprietary.
亚型 IgG
产品特性 Rabbit Polyclonal antibody to JIP1 (mitogen-activated protein kinase 8 interacting protein 1)
JIP1 antibody
纯化方法 Purified by antigen-affinity chromatography.
别名 JIP1 (MAPK8IP1 Antibody 摘要)
背景 The protein encoded by this gene is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.

Cellular Localization: Cytoplasm (By similarity) , Cytoplasm , perinuclear region (By similarity) , Nucleus (By similarity)
分子量 78 kDa
基因ID 9479
应用备注 Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
说明

Positive Control: HepG2

限制 仅限研究用
状态 Liquid
浓度 1 mg/mL
缓冲液 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
储存液 Thimerosal (Merthiolate)
注意事项 This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (Center) antibody (ABIN2854806) WB Image Sample(30 ug whole cell lysate) A:Hep G2 , 7.5% SDS PAGE antibody diluted at...
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (Center) antibody (ABIN2854806) IHC-P Image JIP1 antibody detects JIP1 protein at cytoplasm on mouse brain by immunoh...
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (Center) antibody (ABIN2854806) IHC-P Image Immunohistochemical analysis of paraffin-embedded lung SCC xenograft, usi...
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