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DLK1 抗体 (delta-Like 1 Homolog (Drosophila)) (FITC)

Details for Product anti-DLK1 Antibody No. ABIN2853604, 供应商: Log in to see
抗原
  • DLK
  • DLK-1
  • Delta1
  • FA1
  • PREF1
  • Pref-1
  • ZOG
  • pG2
  • AW742678
  • DlkI
  • Ly107
  • Peg9
  • SCP1
  • pref-1
  • Zog
  • delta-like 1 homolog (Drosophila)
  • DLK1
  • Dlk1
适用
小鼠
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39
2
1
1
1
1
宿主
大鼠
100
57
20
1
克隆类型 (克隆位点)
单克隆 ()
标记
This DLK1 antibody is conjugated to FITC
8
7
6
6
6
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5
4
4
4
4
4
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Flow Cytometry (FACS)
123
77
71
22
13
9
7
6
3
2
2
1
1
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免疫原 Pref-1-Fc protein
克隆位点 24-11-14
亚型 IgG1
特异性 This antibody reacts with Dlk.
交叉反应 (详细) Species reactivity (tested):Mouse.
纯化方法 Protein G Agarose Chromatography of hybridoma supernatant
别名 DLK1 (DLK1 Antibody 摘要)
背景 Delta like protein (Dlk), also known as Preadipocyte factor-1 (Pref-1) or zona glomerulosa-specific factor (ZOG), is an EGF-like transmembrane protein expressed preadipocytes but not in mature adipocytes. It is highly expressed in fetal liver, the adrenal gland, and placenta, as well as some neuroendocrine tumors and small cell lung carcinomas, where it plays a role in differentiation and proliferation. Dlk positively and negatively regulates adipocyte differentiation via at least four major variants (45-60 kDa) of Dlk generated by alternatively splicing. Constitutive expression of Dlk inhibits adipogenesis, but insulin or insulin like growth factor-1 (IGF-1) can circumvent this inhibition. Regulated processing of Dlk releases a 50 kDa soluble form that was previously characterized as Fetal Antigen-1, a protein involved in pancreatic island cell differentiation.Synonyms: DLK, DLK-1, PREF1, Preadipocyte factor 1, Protein delta homolog 1, pG2
基因ID 13386
NCBI登录号 NP_034182
UniProt Q09163
应用备注 Optimal working dilution should be determined by the investigator.
限制 仅限研究用
浓度 0.5 mg/mL
缓冲液 PBS, 0.09 % Sodium Azide, 1 % BSA
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C
储存方法 Store undiluted at 2-8 °C.
厂商提供的图像
Flow Cytometry (FACS) image for anti-DLK1 抗体 (delta-Like 1 Homolog (Drosophila))  (FITC) (ABIN2853604) anti-delta-Like 1 Homolog (Drosophila) (DLK1) antibody (FITC)
背景 Suzuki, Tanaka, Watanabe, Saito, Nonaka, Miyajima: "p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts in mouse fetal liver." in: Gastroenterology, Vol. 135, Issue 1, pp. 270-281.e3, 2008 (PubMed).

Tanimizu, Nishikawa, Saito, Tsujimura, Miyajima: "Isolation of hepatoblasts based on the expression of Dlk/Pref-1." in: Journal of cell science, Vol. 116, Issue Pt 9, pp. 1775-86, 2003 (PubMed).

Kaneta, Osawa, Sudo, Nakauchi, Farr, Takahama: "A role for pref-1 and HES-1 in thymocyte development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 1, pp. 256-64, 2000 (PubMed).