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Desmin 抗体 (pThr17) (Alexa Fluor 594)

DES 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal Alexa Fluor 594
产品编号 ABIN2812346
发货至: 中国
  • 抗原 See all Desmin (DES) 抗体
    Desmin (DES)
    抗原表位
    • 17
    • 17
    • 16
    • 16
    • 14
    • 14
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr17
    适用
    • 149
    • 79
    • 77
    • 33
    • 18
    • 11
    • 11
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 111
    • 37
    • 2
    克隆类型
    • 105
    • 46
    多克隆
    标记
    • 77
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Desmin antibody is conjugated to Alexa Fluor 594
    应用范围
    • 115
    • 69
    • 55
    • 44
    • 27
    • 23
    • 14
    • 13
    • 10
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Cow,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human DES around the phosphorylation site of Thr17
    亚型
    IgG
    Top Product
    Discover our top product DES Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Desmin (DES)
    别名
    Desmin (DES 产品)
    别名
    DES antibody, des-b antibody, MGC80853 antibody, des antibody, csm1 antibody, csm2 antibody, desm antibody, cmd1i antibody, MGC75911 antibody, LOC100220724 antibody, desmin antibody, cb290 antibody, fb59a12 antibody, wu:fb59a12 antibody, zgc:109859 antibody, CSM1 antibody, CSM2 antibody, LGMD2R antibody, wu:fc11d08 antibody, zgc:154009 antibody, des-a antibody, MGC52614 antibody, desmin antibody, desmin, gene 1 L homeolog antibody, desmin, gene 1 antibody, desmin a antibody, desmin b antibody, desmin, gene 1 S homeolog antibody, desmin, gene 2 S homeolog antibody, DES antibody, des.1.L antibody, des.1 antibody, des antibody, desma antibody, Des antibody, desmb antibody, des.1.S antibody, des.2.S antibody
    背景

    Synonyms: Desmin phospho Thr17, Desmin phospho Thr17, CMD1I, CSM1, CSM2, DES, FLJ12025, FLJ39719, FLJ41013, FLJ41793, Intermediate filament protein, OTTHUMP00000064865, DESM_HUMAN

    Background: filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z line structures. Defects in Desmin are the cause of desmin related cardio skeletal myopathy (CSM) also known as desmin related myopathy (DRM). CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by intracytoplasmic accumulation of desmin reactive deposits in cardiac and skeletal muscle cells. A desmin related myopathy can have a distal onset, it is then known as hereditary distal myopathy (HDM). Defects in Desmin are also the cause of dilated cardiomyopathy type 1I (CMD1I). CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function. Antidesmin are useful in identification of tumours of myogenic origin.

    基因ID
    1674
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