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- 抗原 See all SHC3 抗体
- SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SHC3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 亚型
- IgG
- Top Product
- Discover our top product SHC3 Primary Antibody
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- 应用备注
- WB - 1:1000
- 限制
- 仅限研究用
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- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, (2004) (PubMed).
: "ShcB and ShcC activation by the Trk family of receptor tyrosine kinases." in: The Journal of biological chemistry, Vol. 277, Issue 29, pp. 26046-56, (2002) (PubMed).
: "N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway." in: Oncogene, Vol. 13, Issue 6, pp. 1111-21, (1996) (PubMed).
: "A family of Shc related proteins with conserved PTB, CH1 and SH2 regions." in: Oncogene, Vol. 13, Issue 3, pp. 633-41, (1996) (PubMed).
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DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, (2004) (PubMed).
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- 抗原
- SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))
- 别名
- SHC3 (SHC3 产品)
- 别名
- N-Shc antibody, NSHC antibody, RAI antibody, SHCC antibody, ShcC antibody, Rai antibody, SHC adaptor protein 3 antibody, src homology 2 domain-containing transforming protein C3 antibody, SHC3 antibody, Shc3 antibody
- 背景
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Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Synonyms: SHC-transforming protein 3, Neuronal Shc, N-Shc, Protein Rai, SHC-transforming protein C, Src homology 2 domain-containing-transforming protein C3, SH2 domain protein C3, SHC3, NSHC, SHCC - 分子量
- 64056 Da
- 基因ID
- 53358
- UniProt
- Q92529
- 途径
- RTK signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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