NF-kB p65 抗体 (N-Term)
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- 抗原 See all NF-kB p65 (NFkBP65) 抗体
- NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, Cow, 斑马鱼, 马, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NF-kB p65 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VEIIEQPKQR GMRFRYKCEG RSAGSIPGER STDTTKTHPT IKINGYTGPG
- 交叉反应
- 牛, 犬, 小鸡, 人, 小鼠, 猪, 大鼠
- 预测反应
- Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%
- 产品特性
- This is a rabbit polyclonal antibody against RELA. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RELA
- Top Product
- Discover our top product NFkBP65 Primary Antibody
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- 应用备注
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WB Suggested Anti-RELA Antibody Titration: 1.0 µg/mL
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - 说明
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Antigen size: 551 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
- 别名
- RELA / NF-kB p65 (NFkBP65 产品)
- 别名
- C-Rel antibody, NFKB3 antibody, p65 antibody, NFkB antibody, c-rel antibody, zgc:100833 antibody, Xrel2 antibody, Xrel3 antibody, rel antibody, rel-A antibody, rel2 antibody, rel3 antibody, v-rel antibody, xrel antibody, REL proto-oncogene, NF-kB subunit antibody, RELA proto-oncogene, NF-kB subunit antibody, v-rel reticuloendotheliosis viral oncogene homolog A (avian) antibody, v-rel avian reticuloendotheliosis viral oncogene homolog antibody, v-rel avian reticuloendotheliosis viral oncogene homolog L homeolog antibody, REL antibody, RELA antibody, Rela antibody, Rel antibody, rel antibody, rel.L antibody
- 背景
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P65 is a subunit of the nuclear factor kappa-B, a second messenger, which activates the transcription of a number of genes in multiple tissues. The inhibitory effect of I-kappa-B upon NF-kappa-B in the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex.
Alias Symbols: p65, NFKB3
Protein Interaction Partner: GAN, CCND1, ABCA1, UBC, TCF4, SRSF7, RELA, REL, PRKDC, PLG, PEX1, NFKB2, NFKB1, MUC3A, KRT5, REV1, TXN2, FBXW11, IL1RN, IKBKB, HSPA5, HDAC1, EP300, CREBBP, MAP3K8, CHEK1, CDKN2A, CDK4, SPATA31A3, POTEJ, POTEE, PIWIL4, DIS3L2, DCD, IKBKG, CHUK, PLA2G4A, ST
Protein Size: 551 - 分子量
- 60 kDa
- 基因ID
- 5970
- NCBI登录号
- NM_021975, NP_068810
- UniProt
- Q04206
- 途径
- NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
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