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STAT3 抗体 (Middle Region)

STAT3 适用: 人, 小鼠, 大鼠, Cow, 兔, Pig, 犬, 马, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792239
发货至: 中国
  • 抗原 See all STAT3 抗体
    STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
    抗原表位
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    Middle Region
    适用
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    人, 小鼠, 大鼠, Cow, 兔, Pig, 犬, 马, 绵羊, 豚鼠
    宿主
    • 226
    • 58
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    克隆类型
    • 196
    • 94
    多克隆
    标记
    • 162
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    This STAT3 antibody is un-conjugated
    应用范围
    • 216
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    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    FGKYCRPESQ EHPEADPGSA APYLKTKFIC VTPTTCSNTI DLPMSPRTLD
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
    产品特性
    This is a rabbit polyclonal antibody against STAT3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human STAT3
    Top Product
    Discover our top product STAT3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 770 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Suen, Uddin, Prow, Bowen, Hall, Bielefeldt-Ohmann: "Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits." in: Virology, Vol. 494, pp. 1-14, (2016) (PubMed).

  • 抗原
    STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
    别名
    STAT3 (STAT3 产品)
    别名
    1110034C02Rik antibody, AW109958 antibody, Aprf antibody, APRF antibody, HIES antibody, Xstat3 antibody, aprf antibody, hies antibody, stat3 antibody, wu:fc15d02 antibody, wu:fl59g06 antibody, z-Stat3 antibody, signal transducer and activator of transcription 3 antibody, signal transduction and activation of transcription 3 antibody, signal transducer and activator of transcription 3, gene 1 L homeolog antibody, signal transducer and activator of transcription 3 (acute-phase response factor) antibody, STAT3 antibody, stat3 antibody, Stat3 antibody, stat3.1.L antibody
    背景
    STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act a
    Alias Symbols: APRF, FLJ20882, MGC16063, HIES
    Protein Interaction Partner: MTOR, GADD45A, BMX, BLK, UBC, SYK, LMO2, SRI, HIC1, GNB2, USP22, RELA, COPS5, BRD4, ADRB2, PSMG3, TBCD, TBC1D15, PUS7, LUC7L2, ARFIP1, IVNS1ABP, MSH2, BMH1, SIN3A, EGFR, PIAS3, HDAC3, SRC, LYN, JAK3, JAK2, HES5, TRIM28, HES1, HCK, FYN, FGR, HNRNPM, SULT2A
    Protein Size: 770
    分子量
    88 kDa
    基因ID
    6774
    NCBI登录号
    NM_139276, NP_644805
    UniProt
    P40763
    途径
    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
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