Macrophage Scavenger Receptor 1 抗体 (N-Term)
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- 抗原 See all Macrophage Scavenger Receptor 1 (MSR1) 抗体
- Macrophage Scavenger Receptor 1 (MSR1)
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抗原表位
- N-Term
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适用
- 人, Pig, 犬, Cow, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Macrophage Scavenger Receptor 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VSSTNANDIT QSLTGKGNDS EEEMRFQEVF MEHMSNMEKR IQHILDMEAN
- 预测反应
- Cow: 82%, Dog: 93%, Horse: 85%, Human: 100%, Pig: 82%
- 产品特性
- This is a rabbit polyclonal antibody against MSR1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product MSR1 Primary Antibody
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anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 211-320) antibody
MSR1 适用: 人, 小鼠, 绵羊 WB, ELISA, FACS, IHC (fro), IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 275-451) antibodyMSR1 适用: 人 WB, ELISA, FACS, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 5B8H4 unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (N-Term) antibodyMSR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) antibodyMSR1 适用: 人 WB, IHC, IA 宿主: 小鼠 Monoclonal SRA-C6 unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 271-446) antibodyMSR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 121-220) antibodyMSR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) antibodyMSR1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) antibodyMSR1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 85-134) antibodyMSR1 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Scavenger Receptor 1 (MSR1) (AA 300-400) antibodyMSR1 适用: 人, 灵长类, 猴 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 451 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Macrophage Scavenger Receptor 1 (MSR1)
- 别名
- MSR1 (MSR1 产品)
- 背景
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This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.
Alias Symbols: CD204, SCARA1, SR-A, phSR1, phSR2, SRA
Protein Interaction Partner: SEC22A, LEPROTL1, MALL, NKG7, ATP6V0C, IQCB1, TRAF6, HSPA1A,
Protein Size: 451 - 分子量
- 50 kDa
- 基因ID
- 4481
- NCBI登录号
- NM_138715, NP_619729
- UniProt
- P21757
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