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CD33 抗体 (N-Term)

CD33 适用: 人, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789356
发货至: 中国
  • 抗原 See all CD33 抗体
    CD33
    抗原表位
    • 16
    • 16
    • 13
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 162
    • 35
    • 15
    • 13
    • 7
    • 6
    • 2
    人, Cow, 马
    宿主
    • 94
    • 74
    克隆类型
    • 89
    • 78
    • 1
    多克隆
    标记
    • 57
    • 15
    • 13
    • 12
    • 9
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD33 antibody is un-conjugated
    应用范围
    • 104
    • 101
    • 39
    • 30
    • 26
    • 26
    • 23
    • 22
    • 16
    • 13
    • 11
    • 9
    • 6
    • 4
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    HPIPYYDKNS PVHGYWFREG AIISRDSPVA TNKLDQEVQE ETQGRFRLLG
    预测反应
    Cow: 79%, Horse: 79%, Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against CD33. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product CD33 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 364 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CD33
    别名
    CD33 (CD33 产品)
    别名
    SIGLEC-3 antibody, SIGLEC3 antibody, p67 antibody, Siglec-3 antibody, gp67 antibody, CD33 molecule antibody, CD33 antigen antibody, CD33 antibody, Cd33 antibody
    背景
    CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia (in vitro).
    Alias Symbols: FLJ00391, SIGLEC-3, SIGLEC3, p67
    Protein Interaction Partner: KRT40, KRT31, HERC3, UBC, CBL, SRC, PTPN6, PTPN11,
    Protein Size: 364
    分子量
    38 kDa
    基因ID
    945
    NCBI登录号
    NM_001772, NP_001763
    UniProt
    P20138
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