PPP1CA 抗体 (N-Term)
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- 抗原 See all PPP1CA 抗体
- PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PPP1CA antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MSDSEKLNLD SIIGRLLEGS RVLTPHCAPV QGSRPGKNVQ LTENEIRGLC
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against PPP1CA. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PPP1CA
- Top Product
- Discover our top product PPP1CA Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 341 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
- 别名
- PPP1CA (PPP1CA 产品)
- 别名
- PP-1A antibody, PP1A antibody, PP1alpha antibody, PPP1A antibody, Ppp1c antibody, dism2 antibody, ppp1a antibody, wu:fc04c08 antibody, wu:fc09b07 antibody, wu:fc30g11 antibody, wu:fe05h08 antibody, zgc:85729 antibody, Ppp1ca antibody, fb18b03 antibody, fd20h04 antibody, wu:fb18b03 antibody, wu:fd20h04 antibody, wu:fl22a03 antibody, zgc:55744 antibody, zgc:76940 antibody, protein phosphatase 1 catalytic subunit alpha antibody, protein phosphatase 1, catalytic subunit, alpha isoform antibody, protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog antibody, protein phosphatase 1, catalytic subunit, alpha isozyme antibody, protein phosphatase 1, catalytic subunit, alpha isozyme a antibody, protein phosphatase 1, catalytic subunit, alpha isozyme b antibody, PPP1CA antibody, Ppp1ca antibody, ppp1ca.L antibody, ppp1ca antibody, ppp1caa antibody, ppp1cab antibody
- 背景
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PPP1CA is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory.The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC15877, MGC1674, PP-1A, PPP1A, PP1alpha
Protein Interaction Partner: HUWE1, PPP1R2P3, CSRNP2, CSRNP1, UBC, SUMO2, SUMO3, BRCA1, Kctd20, WWOX, PKM, SCPEP1, TMOD3, MAT2B, STK24, YWHAH, XPO1, TBCB, CAPNS1, ALDH7A1, ASNS, YAP1, LMTK2, RB1, POLR2A, GSK3B, MST1R, IKBKB, CHUK, CTDP1, TNFRSF1A, tat, PPP1R15A, PPP1R13B, PLCL2, CD2B
Protein Size: 341 - 分子量
- 38 kDa
- 基因ID
- 5499
- NCBI登录号
- NM_001008709, NP_001008709
- UniProt
- Q07161
- 途径
- M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism
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