alpha KGDHC 抗体 (N-Term)
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- 抗原 See all alpha KGDHC (alphaKGDHC) 抗体
- alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
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抗原表位
- N-Term
- 适用
- 人, 大鼠, 小鼠, Cow, 马, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This alpha KGDHC antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MFHLRTCAAK LRPLTASQTV KTFSQNRPAA ARTFQQIRCY SAPVAAEPFL
- 预测反应
- Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against OGDH. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human OGDH
- Top Product
- Discover our top product alphaKGDHC Primary Antibody
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anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 148-427) antibody
alphaKGDHC 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (C-Term) antibodyalphaKGDHC 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) antibodyalphaKGDHC 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (N-Term) antibodyalphaKGDHC 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 41-423) antibodyalphaKGDHC 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (N-Term) antibodyalphaKGDHC 适用: 人, Cow, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 256-582) antibodyalphaKGDHC 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 381-410), (C-Term) antibodyalphaKGDHC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32469 unconjugated
anti-alpha Ketoglutarate Dehydrogenase (alphaKGDHC) antibodyalphaKGDHC 适用: 人, 大鼠, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 427 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
- 别名
- OGDH (alphaKGDHC 产品)
- 别名
- AKGDH antibody, E1k antibody, OGDC antibody, 2210403E04Rik antibody, 2210412K19Rik antibody, AA409584 antibody, d1401 antibody, mKIAA4192 antibody, oxoglutarate dehydrogenase antibody, oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) antibody, OGDH antibody, Ogdh antibody
- 背景
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The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
Alias Symbols: AKGDH, E1k, OGDC
Protein Interaction Partner: MDM2, UBC, SUMO1, NEDD8, CPSF7, MRPL38, MRPL41, TSR1, MRPS2, MRPL15, MRPL13, SCFD1, PDHX, SSBP1, SUMO2, PDHB, PDHA1, DLST, DLAT, DHODH, ISG15, USP13, PLSCR1, DLD,
Protein Size: 427 - 分子量
- 47 kDa
- 基因ID
- 4967
- NCBI登录号
- NM_001003941, NP_001003941
- UniProt
- Q96DD3
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