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PNPO 抗体 (N-Term)

PNPO 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787718
发货至: 中国
  • 抗原 See all PNPO 抗体
    PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))
    抗原表位
    • 15
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠
    宿主
    • 40
    • 9
    克隆类型
    • 42
    • 7
    多克隆
    标记
    • 22
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PNPO antibody is un-conjugated
    应用范围
    • 30
    • 22
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    PMRKSYRGDR EAFEETHLTS LDPVKQFAAW FEEAVQCPDI GEANAMCLAT
    预测反应
    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against PNPO. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human PNPO
    Top Product
    Discover our top product PNPO Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 261 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Song, Ueno, Numata, Iga, Shibuya-Tayoshi, Nakataki, Tayoshi, Yamauchi, Sumitani, Tomotake, Tada, Tanahashi, Itakura, Ohmori: "Association between PNPO and schizophrenia in the Japanese population." in: Schizophrenia research, Vol. 97, Issue 1-3, pp. 264-70, (2007) (PubMed).

  • 抗原
    PNPO (Pyridoxamine 5'-Phosphate Oxidase (PNPO))
    别名
    PNPO (PNPO 产品)
    别名
    im:7138360 antibody, ECK1634 antibody, JW1630 antibody, PDXPO antibody, AI415282 antibody, pyridoxamine 5'-phosphate oxidase antibody, pyridoxine 5'-phosphate oxidase antibody, Pyridoxamine 5'-phosphate oxidase antibody, pnpo antibody, pdxH antibody, Mrub_2888 antibody, Arnit_1624 antibody, Ndas_4168 antibody, Mesil_2817 antibody, Isop_0296 antibody, Despr_1960 antibody, Pedsa_1348 antibody, Mesop_5639 antibody, PNPO antibody, Pnpo antibody
    背景
    PNPO catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.Vitamin B6, or pyridoxal 5-prime-phosphate (PLP), is critical for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. The rate-limiting enzyme in vitamin B6 synthesis is pyridoxine-5-prime-phosphate (PNP) oxidase (PNPO, EC 1.4.3.5).[supplied by OMIM].
    Alias Symbols: FLJ10535, PDXPO
    Protein Interaction Partner: UBC, LPP, APP, ELAVL1,
    Protein Size: 261
    分子量
    29 kDa
    基因ID
    55163
    NCBI登录号
    NM_018129, NP_060599
    UniProt
    Q9NVS9
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