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UBE2K 抗体 (Middle Region)

UBE2K 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 山羊, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787511
发货至: 中国
  • 抗原 See all UBE2K 抗体
    UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
    抗原表位
    • 8
    • 8
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 46
    • 21
    • 18
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 山羊, 马, 兔, 豚鼠
    宿主
    • 43
    • 2
    • 2
    • 1
    克隆类型
    • 46
    • 2
    多克隆
    标记
    • 25
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2K antibody is un-conjugated
    应用范围
    • 37
    • 26
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    TVLLSLQALL AAAEPDDPQD AVVANQYKQN PEMFKQTARL WAHVYAGAPV
    预测反应
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against UBE2K. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human UBE2K
    Top Product
    Discover our top product UBE2K Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 200 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
    别名
    UBE2K (UBE2K 产品)
    别名
    E2-25K antibody, HIP2 antibody, HYPG antibody, LIG antibody, UBC1 antibody, E2-25k antibody, Hip2 antibody, Hypg antibody, Lig antibody, e2-25k antibody, hip2 antibody, hypg antibody, lig antibody, AW492011 antibody, D5Ertd601e antibody, ube2k antibody, zgc:103472 antibody, zgc:110791 antibody, ubiquitin conjugating enzyme E2 K antibody, ubiquitin-conjugating enzyme E2K antibody, ubiquitin conjugating enzyme E2 K S homeolog antibody, ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) antibody, ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) antibody, UBE2K antibody, Ube2k antibody, ube2k.S antibody, ube2k antibody, ube2kb antibody, ube2ka antibody
    背景
    UBE2K belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
    Alias Symbols: DKFZp564C1216, DKFZp686J24237, E2-25K, HIP2, HYPG, LIG, UBC1
    Protein Interaction Partner: DDI1, DTX3, MIPOL1, TRIM39, ANAPC11, RNF138, SIAH1, RNF5, REL, FZR1, UBC, UBA1, MARCH7, AMFR, TP53, MDM2, BAG3, PRRG4, IQCB1, HTT, CDC6, WDR1, TYMS, TXN, TXNDC17, WDR61, ITCH, NEDD4L, WWP2, NXF1, NUB1, PIAS4, CASP12, SUMO1, SUMO2, DIABLO, UBE2I, CCNB1, BR
    Protein Size: 200
    分子量
    22 kDa
    基因ID
    3093
    NCBI登录号
    NM_005339, NP_005330
    UniProt
    P61086
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