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Metabotropic Glutamate Receptor 6 抗体 (N-Term)

GRM6 适用: 人, 大鼠, 小鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼, Pig, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787505
发货至: 中国
  • 抗原 See all Metabotropic Glutamate Receptor 6 (GRM6) 抗体
    Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
    抗原表位
    • 14
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 47
    • 16
    • 15
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼, Pig, 绵羊
    宿主
    • 46
    • 3
    克隆类型
    • 47
    • 2
    多克隆
    标记
    • 26
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Metabotropic Glutamate Receptor 6 antibody is un-conjugated
    应用范围
    • 35
    • 25
    • 13
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    序列
    AGGLTLGGLF PVHARGAAGR ACGQLKKEQG VHRLEAMLYA LDRVNADPEL
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%, Sheep: 79%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against GRM6. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human GRM6
    Top Product
    Discover our top product GRM6 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 877 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
    别名
    GRM6 (GRM6 产品)
    别名
    mGluR6 antibody, CSNB1B antibody, GPRC1F antibody, MGLUR6 antibody, mGlu6 antibody, GRM6 antibody, BC021919 antibody, Gm3 antibody, Gprc1f antibody, nerg1 antibody, nob2 antibody, nob3 antibody, nob4 antibody, si:dkey-52h10.3 antibody, cb496 antibody, grma antibody, zK13A21.16 antibody, zgc:158329 antibody, glutamate metabotropic receptor 6 antibody, glutamate receptor, metabotropic 6 antibody, glutamate receptor, metabotropic 6a antibody, glutamate receptor, metabotropic 6b antibody, Grm6 antibody, GRM6 antibody, grm6a antibody, grm6b antibody
    背景
    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
    Alias Symbols: CSNB1B, DKFZp686H1993, GPRC1F, MGLUR6, mGlu6
    Protein Interaction Partner: GNAO1,
    Protein Size: 877
    分子量
    95 kDa
    基因ID
    2916
    NCBI登录号
    NM_000843, NP_000834
    UniProt
    O15303
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