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NKIRAS1 抗体 (N-Term)

NKIRAS1 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2786171
发货至: 中国
  • 抗原 See all NKIRAS1 抗体
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 41
    • 30
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 山羊, 豚鼠, 马, 兔, 斑马鱼
    宿主
    • 49
    • 7
    克隆类型
    • 49
    • 7
    多克隆
    标记
    • 22
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NKIRAS1 antibody is un-conjugated
    应用范围
    • 46
    • 27
    • 13
    • 13
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    CETMEDVYMA SVETDRGVKE QLHLYDTRGL QEGVELPKHY FSFADGFVLV
    预测反应
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against NKIRAS1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human NKIRAS1
    Top Product
    Discover our top product NKIRAS1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 192 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
    别名
    NKIRAS1 (NKIRAS1 产品)
    别名
    NKIRAS1 antibody, KBRAS1 antibody, kappaB-Ras1 antibody, zgc:92823 antibody, kbras1 antibody, 2400004O09Rik antibody, NFKB inhibitor interacting Ras like 1 antibody, NFKB inhibitor interacting Ras-like 1 antibody, NFKB inhibitor interacting Ras-like 1 S homeolog antibody, NFKB inhibitor interacting Ras-like protein 1 antibody, NKIRAS1 antibody, nkiras1 antibody, nkiras1.S antibody, Nkiras1 antibody
    背景
    NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
    Alias Symbols: KBRAS1, kappaB-Ras1
    Protein Interaction Partner: XRCC2, UBC, APP, NFKBIB, SMURF2, BMPR1B, TGFBR1, NFKBIA, ACVR1,
    Protein Size: 192
    分子量
    22 kDa
    基因ID
    28512
    NCBI登录号
    NM_020345, NP_065078
    UniProt
    Q9NYS0
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