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Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1) (Middle Region) 抗体

ABIN2785912 产品详细信息, 供应商: Log in to see
抗原
  • APPL
  • DIP13alpha
  • 2900057D21Rik
  • 7330406P05Rik
  • AI585782
  • AW209077
  • BB022931
  • C88264
  • DIP13
  • RGD1309388
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • APPL1
  • Appl1
抗原表位
Middle Region
15
9
5
5
4
3
2
2
2
2
1
1
1
1
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠
64
32
20
6
4
3
3
2
2
2
1
1
宿主

43
20
3
克隆类型
多克隆
标记
非结合性
1
1
1
1
1
1
应用范围
Western Blotting (WB)
60
33
17
12
3
3
1
1
1
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免疫原 The immunogen is a synthetic peptide directed towards the middle region of human APPL1
Blocking Peptide Blocking peptide for this product available: ABIN973345
序列 GQAKAFGQGG RRTNPFGESG GSTKSETEDS ILHQLFIVRF LGSMEVKSDD
预测反应 Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 75%, Rat: 100%
产品特性 This is a rabbit polyclonal antibody against APPL1. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
别名 APPL1 (APPL1 Antibody 摘要)
背景 The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A
Alias Symbols: APPL, DIP13alpha
Protein Interaction Partner: RHEBL1, UBE2O, APPL2, APPL1, FARS2, MEOX1, MAGEA9, UBC, KIAA1468, CLUH, TTC4, TRAF6, ADIPOR1, HDAC5, HDAC3, HDAC2, PIK3R1, AR, AKT1, CMTM4, PLEKHF2, KXD1, DPYSL5, EGFR, RAB21, VCP, RAB5A, AKT2, ADIPOR2, FSHR, ELAVL1, MTA2, RBBP7, RUVBL2, RBBP4, HDAC1, TRA
Protein Size: 709
分子量 80 kDa
基因ID 26060
NCBI登录号 NM_012096, NP_036228
UniProt Q9UKG1
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 709 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1) (Middle Region) 抗体 (ABIN2785912) WB Suggested Anti-APPL1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive...
背景 McCrea, Paradise, Tomasini, Addis, Melis, De Matteis, De Camilli: "All known patient mutations in the ASH-RhoGAP domains of OCRL affect targeting and APPL1 binding." in: Biochemical and biophysical research communications, Vol. 369, Issue 2, pp. 493-9, 2008 (PubMed).