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LIF 抗体 (N-Term)

LIF 适用: 人, 小鼠, 大鼠, Cow, 犬, 绵羊, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2785833
发货至: 中国
  • 抗原 See all LIF 抗体
    LIF (Leukemia Inhibitory Factor (LIF))
    抗原表位
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 45
    • 15
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 绵羊, 豚鼠, 马, 兔
    宿主
    • 42
    • 8
    • 2
    • 2
    • 2
    • 1
    克隆类型
    • 51
    • 6
    多克隆
    标记
    • 39
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIF antibody is un-conjugated
    应用范围
    • 46
    • 26
    • 24
    • 14
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    KVLAAGVVPL LLVLHWKHGA GSPLPITPVN ATCAIRHPCH NNLMNQIRSQ
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 86%
    产品特性
    This is a rabbit polyclonal antibody against LIF. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human LIF
    Top Product
    Discover our top product LIF Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 202 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Muntz, Malpass, McGonigle, Robertson, Weiden: "Phase 2 study of intraperitoneal topotecan as consolidation chemotherapy in ovarian and primary peritoneal carcinoma." in: Cancer, Vol. 113, Issue 3, pp. 490-6, (2008) (PubMed).

  • 抗原
    LIF (Leukemia Inhibitory Factor (LIF))
    别名
    LIF (LIF 产品)
    别名
    CDF antibody, DIA antibody, HILDA antibody, MLPLI antibody, LIF, interleukin 6 family cytokine antibody, leukemia inhibitory factor antibody, LIF antibody, Lif antibody
    背景
    LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface.Leukaemia inhibitory factor is a cytokine that induces macrophage differentiation. Neurotransmitters and neuropeptides, well known for their role in the communication between neurons, are also capable of activating monocytes and macrophages and inducing chemotaxis in immune cells. LIF signals through different receptors and transcription factors. LIF in conjunction with BMP2 acts in synergy on primary fetal neural progenitor cells to induce astrocytes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CDF, D-FACTOR, HILDA, DIA
    Protein Interaction Partner: IL6ST, LIFR,
    Protein Size: 202
    分子量
    22 kDa
    基因ID
    3976
    NCBI登录号
    NM_002309, NP_002300
    UniProt
    P15018
    途径
    JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding
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